Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99593 / TBX5_HUMAN
Protein Name T-box transcription factor TBX5
Gene Name Name: TBX5
Organism Homo sapiens (Human)

PRO ID PR:Q99593
DAG View
PRO Name T-box transcription factor TBX5 (human)
Definition A T-box transcription factor TBX5 that is encoded in the genome of human.
Short Label hTBX5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99593 (TBX5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T13 Phosphorylation PhosphoSitePlus
T92 Phosphorylation PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
K339 Acetylation UniProt 29174768
Y342 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
Y354 Phosphorylation PhosphoSitePlus
Y358 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T13 M13 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ tcga ]
T92 K92 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
T92 M92 Biomuta DOID:363 / uterine cancer [ tcga ]
S252 R252 Biomuta DOID:1612 / breast cancer [ tcga ] DOID:3371 / chondrosarcoma [ cosmic ]