iPTMnet Report for Q99593 (TBX5)
Protein Information
| UniProt AC / UniProt ID | Q99593 / TBX5_HUMAN |
| Protein Name | T-box transcription factor TBX5 |
| Gene Name | Name: TBX5 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q99593 |
| PRO Name | T-box transcription factor TBX5 (human) |
| Definition | A T-box transcription factor TBX5 that is encoded in the genome of human. |
| Short Label | hTBX5 |
| Category | organism-gene |
DAG ViewQ99593 (TBX5) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T92 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y114 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y217 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S252 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y255 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S261 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T262 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K339 | Acetylation | score2 | UniProt | 29174768 | ||
| Y342 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S352 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y354 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y358 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T13 | M13 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| T92 | K92 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T92 | M92 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| S252 | R252 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
| S352 | F352 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
