iPTMnet Report for Q99576 (TSC22D3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99576 / T22D3_HUMAN
Protein Name TSC22 domain family protein 3
Gene Name Name: TSC22D3
Synonyms:DSIPI;
Organism Homo sapiens (Human)

PRO ID PR:Q99576
DAG View
PRO Name TSC22 domain family protein 3 (human)
Definition A TSC22 domain family protein 3 that is encoded in the genome of human.
Short Label hTSC22D3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99576 (TSC22D3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A42 Phosphorylation UniProt 18669648
K53 Ubiquitination PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
V73 Phosphorylation UniProt 18669648
K77 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus   UniProt 23186163
K108 Ubiquitination PhosphoSitePlus
S122 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
Site PTM Type PTM Enzyme Score Source PMID
S122 Phosphorylation HPRD 19413330, 18088087
S132 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
R31 Methylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
S42 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18669648, 20068231
K54 Ubiquitination PhosphoSitePlus
S73 Phosphorylation HPRD   PhosphoSitePlus 18669648
S188 Phosphorylation HPRD 19413330, 18088087
S198 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S65 Phosphorylation HPRD 19413330, 18088087
S75 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S34 N34 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
V73 M73 Biomuta DOID:1612 / breast cancer [ cosmic ]
S73 L73 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K98 N98 Biomuta DOID:1324 / lung cancer [ cosmic ]
S122 T122 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S188 T188 Biomuta DOID:10534 / stomach cancer [ cosmic ]