iPTMnet Report for Q99572 (P2RX7)
Protein Information
| UniProt AC / UniProt ID | Q99572 / P2RX7_HUMAN |
| Protein Name | P2X purinoceptor 7 |
| Gene Name | Name: P2RX7 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q99572 |
| PRO Name | P2X purinoceptor 7 (human) |
| Definition | A P2X purinoceptor 7 that is encoded in the genome of human. |
| Short Label | hP2RX7 |
| Category | organism-gene |
DAG ViewQ99572 (P2RX7) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N187 | N-Glycosylation | score4 | GlyGen UniProt | 20450227, 29741879 | ||
| N202 | N-Glycosylation | score3 | GlyGen UniProt | 20450227 | ||
| N213 | N-Glycosylation | score4 | GlyGen UniProt | 20450227, 24190977 | ||
| N241 | N-Glycosylation | score3 | GlyGen UniProt | 20450227 | ||
| N284 | N-Glycosylation | score3 | GlyGen UniProt | 20450227 | ||
| Y343 | Phosphorylation | score3 | phospho.ELM UniProt | 11707406 | ||
| S390 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| T449 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y588 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | P49023 (PXN) | Y31 | Q99572 (P2RX7) | unknown | eFIP | 33243234 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N241 | S241 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
