Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99571 / P2RX4_HUMAN
Protein Name P2X purinoceptor 4
Gene Name Name: P2RX4
Organism Homo sapiens (Human)

PRO ID PR:Q99571
DAG View
PRO Name P2X purinoceptor 4 (human)
Definition A P2X purinoceptor 4 that is encoded in the genome of human.
Short Label hP2RX4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99571 (P2RX4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N75 N-Glycosylation GlyGen 29741879, 24190977
S128 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
T146 Phosphorylation PhosphoSitePlus
N153 N-Glycosylation GlyGen 29741879, 24190977
N184 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
N208 N-Glycosylation GlyGen 29741879, 24190977
S289 Phosphorylation PhosphoSitePlus
Y292 Phosphorylation PhosphoSitePlus
Y299 Phosphorylation PhosphoSitePlus
Y300 Phosphorylation PhosphoSitePlus
S384 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S141 I141 Biomuta DOID:363 / uterine cancer [ tcga ]
Y292 C292 Biomuta DOID:2531 / hematologic cancer [ tcga ]
Y299 H299 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S384 G384 Biomuta DOID:10283 / prostate cancer [ cosmic ]