iPTMnet Report for Q99571 (P2RX4)
Protein Information
| UniProt AC / UniProt ID | Q99571 / P2RX4_HUMAN |
| Protein Name | P2X purinoceptor 4 |
| Gene Name | Name: P2RX4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q99571 |
| PRO Name | P2X purinoceptor 4 (human) |
| Definition | A P2X purinoceptor 4 that is encoded in the genome of human. |
| Short Label | hP2RX4 |
| Category | organism-gene |
DAG ViewQ99571 (P2RX4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N75 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
| S128 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T146 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N153 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
| N184 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218, 24190977 | ||
| N208 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
| S289 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y292 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y299 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y300 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S384 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S141 | I141 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T146 | I146 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| Y292 | C292 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| Y299 | H299 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S384 | G384 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] |
