iPTMnet Report for Q99543 (DNAJC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99543 / DNJC2_HUMAN
Protein Name DnaJ homolog subfamily C member 2
Gene Name Name: DNAJC2
Synonyms:MPHOSPH11,MPP11,ZRF1;
Organism Homo sapiens (Human)

PRO ID PR:Q99543
DAG View
PRO Name DnaJ homolog subfamily C member 2 (human)
Definition A DnaJ homolog subfamily C member 2 that is encoded in the genome of human.
Short Label hDNAJC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99543 (DNAJC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22223895
K40 Ubiquitination PhosphoSitePlus
S47 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 23186163, 17081983, ...28242756, 18669648, 17287340, 19690332, 20068231
S49 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 17287340, 20068231
S60 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S63 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
Y90 Phosphorylation PhosphoSitePlus
Y100 Phosphorylation PhosphoSitePlus
T103 O-Glycosylation GlyGen 30379171
K112 Ubiquitination PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
T183 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
Y274 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
T539 Phosphorylation PhosphoSitePlus
Y548 Phosphorylation PhosphoSitePlus
K567 Ubiquitination PhosphoSitePlus
T573 Phosphorylation PhosphoSitePlus
K606 Methylation PhosphoSitePlus
K607 Methylation PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S47 Phosphorylation HPRD 17287340, 17081983, 18767875, ...19664994, 18452278, 19651622, 18669648, 20068231
S49 Phosphorylation HPRD 17287340, 17081983, 19664994, ...19651622, 18669648, 20068231
S60 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
S63 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S63 L63 Biomuta DOID:4159 / skin cancer [ cosmic ]
S63 * Biomuta DOID:263 / kidney cancer [ cosmic ]
Y100 C100 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T103 K103 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y137 C137 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T142 A142 Biomuta [ cosmic ]
K175 N175 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T183 N183 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
Y274 H274 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S367 F367 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T539 M539 Biomuta DOID:9256 / colorectal cancer [ cosmic ]