iPTMnet Report for Q99541 (PLIN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99541 / PLIN2_HUMAN
Protein Name Perilipin-2
Gene Name Name: PLIN2
Synonyms:ADFP;
Organism Homo sapiens (Human)

PRO ID PR:Q99541
DAG View
PRO Name perilipin-2 (human)
Definition A perilipin-2 that is encoded in the genome of human.
Short Label hPLIN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99541 (PLIN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
K116 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y216 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
K226 Acetylation PhosphoSitePlus
Y232 Phosphorylation P35790 (CHKA) PhosphoSitePlus   Signor   UniProt 34077757, 34929314
S237 Phosphorylation PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
C325 Methylation IEDB 31844290
S362 Phosphorylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K116 N116 Biomuta DOID:363 / uterine cancer [ icgc ]
Y217 F217 Biomuta DOID:3571 / liver cancer [ cosmic ]