iPTMnet Report for Q99502 (EYA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99502 / EYA1_HUMAN
Protein Name Eyes absent homolog 1
Gene Name Name: EYA1
Organism Homo sapiens (Human)

PRO ID PR:Q99502
DAG View
PRO Name eyes absent homolog 1 (human)
Definition An eyes absent homolog 1 that is encoded in the genome of human.
Short Label hEYA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99502 (EYA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S19 Phosphorylation PhosphoSitePlus
K43 Sumoylation PhosphoSitePlus
K147 Sumoylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus 24954506
S299 Phosphorylation P31749 (AKT1) PhosphoSitePlus 24954506
S303 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
K460 Acetylation PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S314 Phosphorylation HPRD 18767875, 19664994
Site PTM Type PTM Enzyme Score Source PMID
S281 Phosphorylation HPRD 18767875, 19664994


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047341 (hEYA1/PhosRes+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S281 A281 Biomuta DOID:3571 / liver cancer [ cosmic ]
S299 L299 Biomuta DOID:1612 / breast cancer [ cosmic ]
S314 A314 Biomuta DOID:3571 / liver cancer [ cosmic ]
S319 F319 Biomuta DOID:4159 / skin cancer [ cosmic ]
S319 Y319 Biomuta DOID:363 / uterine cancer [ cosmic ]
K534 N534 Biomuta DOID:10534 / stomach cancer [ cosmic ]