iPTMnet Report Q99497 PARK7

Protein Information

UniProt AC / UniProt ID	Q99497 / PARK7_HUMAN
Protein Name	Parkinson disease protein 7 precursor
Gene Name	Name: PARK7
Organism	Homo sapiens (Human)

PRO ID	PR:Q99497 DAG View
PRO Name	parkinson disease protein 7 (human)
Definition	A parkinson disease protein 7 that is encoded in the genome of human.
Short Label	hPARK7
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q99497 (PARK7) as Substrate

Q99497

Condensed View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position A2 T19 R27 K32 K41 C46 S47 C53 S57 K62 K63 Y67 K89 K93 K99 T125 K130 K132 Y139 Y141 S142 K148 T154 K175 K182 K188	PTM Type Select all Acetylation Methylation Phosphorylation S-Nitrosylation Sumoylation Ubiquitination	Score Select all 0 1 2 3	Source Select all HPRD PhosphoSitePlus RLIMS-P UniProt dbSNO phospho.ELM	PMID
A2	Acetylation	score1	UniProt	25944712
T19	Phosphorylation	score1	PhosphoSitePlus
R27	Methylation	score1	PhosphoSitePlus
K32	Ubiquitination	score1	PhosphoSitePlus
K41	Acetylation	score1	PhosphoSitePlus
K41	Ubiquitination	score1	PhosphoSitePlus
C46	S-Nitrosylation	score0	dbSNO	26338901, 24105792
S47	Phosphorylation	score1	PhosphoSitePlus
C53	S-Nitrosylation	score0	dbSNO	19483679, 26338901
S57	Phosphorylation	score1	PhosphoSitePlus
K62	Acetylation	score1	PhosphoSitePlus
K62	Ubiquitination	score1	PhosphoSitePlus
K63	Acetylation	score1	PhosphoSitePlus
K63	Ubiquitination	score1	PhosphoSitePlus
Y67	Phosphorylation	score2	HPRD phospho.ELM PhosphoSitePlus UniProt	15592455
K89	Ubiquitination	score1	PhosphoSitePlus
K93	Ubiquitination	score1	PhosphoSitePlus
K99	Ubiquitination	score1	PhosphoSitePlus
T125	Phosphorylation	score3	PhosphoSitePlus RLIMS-P	32858971
K130	Acetylation	score1	PhosphoSitePlus
K130	Sumoylation	score1	PhosphoSitePlus
K130	Ubiquitination	score1	PhosphoSitePlus
K132	Acetylation	score1	PhosphoSitePlus
Y139	Phosphorylation	score1	PhosphoSitePlus
Y141	Phosphorylation	score1	PhosphoSitePlus
S142	Phosphorylation	score0	HPRD	20068231
K148	Acetylation	score1	PhosphoSitePlus
K148	Ubiquitination	score1	PhosphoSitePlus
T154	Phosphorylation	score1	PhosphoSitePlus
K175	Ubiquitination	score1	PhosphoSitePlus
K182	Ubiquitination	score1	PhosphoSitePlus
K188	Ubiquitination	score1	PhosphoSitePlus

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine By position T19 R27 S47 K99 T154 K175	Variant Select all A19 G27 I154 M19 R47 R99 T175	Source Select all Biomuta	Disease [Sample source] Select all DOID:10534 / stomach cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]
T19	M19	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
T19	A19	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ]
R27	G27	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
S47	R47	Biomuta	DOID:4159 / skin cancer [ cosmic ]
K99	R99	Biomuta	DOID:1781 / thyroid gland cancer [ cosmic ]
T154	I154	Biomuta	DOID:1612 / breast cancer [ cosmic ]
K175	T175	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q99497 (PARK7)

Protein Information

Interactive Sequence View

Q99497 (PARK7) as Substrate

PTM sites affected in variants