Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99460 / PSMD1_HUMAN
Protein Name 26S proteasome non-ATPase regulatory subunit 1
Gene Name Name: PSMD1
Organism Homo sapiens (Human)

PRO ID PR:Q99460
DAG View
PRO Name 26S proteasome non-ATPase regulatory subunit 1 (human)
Definition A 26S proteasome non-ATPase regulatory subunit 1 that is encoded in the genome of human.
Short Label hPSMD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99460 (PSMD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22223895
K20 Ubiquitination PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
Y49 Phosphorylation phospho.ELM   PhosphoSitePlus 16097034
K110 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
Y147 Phosphorylation PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
R199 Methylation PhosphoSitePlus
T270 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T273 Phosphorylation Q16539 (MAPK14) neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 17323924, ...18669648, 21044959
S277 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
T284 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S290 Phosphorylation PhosphoSitePlus   UniProt 17323924
K292 Ubiquitination PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S296 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T299 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K302 Ubiquitination PhosphoSitePlus
T303 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
K310 Acetylation PhosphoSitePlus   UniProt 19608861
K310 Sumoylation PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
T311 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...15302935, 17323924, 18669648, 19690332
S315 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...15302935, 17323924, 18669648, 19690332
K319 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
T348 Phosphorylation PhosphoSitePlus
K354 Ubiquitination PhosphoSitePlus
K401 Acetylation PhosphoSitePlus
K413 Acetylation PhosphoSitePlus
K417 Acetylation PhosphoSitePlus
K417 Ubiquitination PhosphoSitePlus
T488 Phosphorylation PhosphoSitePlus
Y494 Phosphorylation PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
K574 Ubiquitination PhosphoSitePlus
K597 Ubiquitination PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
Y713 Phosphorylation PhosphoSitePlus
K715 Ubiquitination PhosphoSitePlus
K720 Acetylation PhosphoSitePlus
K720 Ubiquitination PhosphoSitePlus
K799 Ubiquitination PhosphoSitePlus
K803 Ubiquitination PhosphoSitePlus
K807 Ubiquitination PhosphoSitePlus
Y813 Phosphorylation PhosphoSitePlus
K821 Ubiquitination PhosphoSitePlus
K825 Ubiquitination PhosphoSitePlus
K827 Ubiquitination PhosphoSitePlus
T830 Phosphorylation PhosphoSitePlus   UniProt 23186163
S834 Phosphorylation PhosphoSitePlus   UniProt 23186163
K838 Ubiquitination PhosphoSitePlus
K840 Ubiquitination PhosphoSitePlus
K849 Acetylation PhosphoSitePlus
K853 Ubiquitination PhosphoSitePlus
K861 Ubiquitination PhosphoSitePlus
K862 Ubiquitination PhosphoSitePlus
K865 Ubiquitination PhosphoSitePlus
K868 Ubiquitination PhosphoSitePlus
K869 Ubiquitination PhosphoSitePlus
K890 Ubiquitination PhosphoSitePlus
Y900 Phosphorylation PhosphoSitePlus
K904 Ubiquitination PhosphoSitePlus
K915 Ubiquitination PhosphoSitePlus
K934 Sumoylation PhosphoSitePlus
K934 Ubiquitination PhosphoSitePlus
Y950 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T157 Phosphorylation HPRD 20068231, 20068230
Y179 Phosphorylation HPRD 20068231
T270 Phosphorylation HPRD 18669648, 20068231
T273 Phosphorylation HPRD 19413330, 20058876, 19664994, ...15302935, 19664995, 18669648, 19415658, 20068231
T284 Phosphorylation HPRD 18669648
S296 Phosphorylation HPRD 18669648
T299 Phosphorylation HPRD 18669648
S305 Phosphorylation HPRD 17081983
T311 Phosphorylation HPRD 19413330, 16964243, 18767875, ...19664994, 19651622, 15302935, 18669648, 20166139, 19415658
S315 Phosphorylation HPRD 19413330, 16964243, 18767875, ...19664994, 19651622, 15302935, 18669648, 20166139, 19415658
T488 Phosphorylation HPRD 20068230


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T284 M284 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S305 I305 Biomuta DOID:3571 / liver cancer [ icgc ]
K310 * Biomuta DOID:263 / kidney cancer [ cosmic ]
K310 N310 Biomuta DOID:1612 / breast cancer [ cosmic ]
K413 N413 Biomuta DOID:3571 / liver cancer [ icgc ]
S834 P834 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]