iPTMnet Report for Q99447 (PCYT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99447 / PCY2_HUMAN
Protein Name Ethanolamine-phosphate cytidylyltransferase
Gene Name Name: PCYT2
Organism Homo sapiens (Human)

PRO ID PR:Q99447
DAG View
PRO Name ethanolamine-phosphate cytidylyltransferase (human)
Definition An ethanolamine-phosphate cytidylyltransferase that is encoded in the genome of human.
Short Label hPCYT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99447 (PCYT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R6 Methylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
T146 Phosphorylation PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
Y170 Phosphorylation PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus   UniProt 24275569
T341 Phosphorylation PhosphoSitePlus   UniProt 23186163
T342 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T141 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T141 M141 Biomuta DOID:363 / uterine cancer [ icgc ]
S145 F145 Biomuta DOID:4159 / skin cancer [ cosmic ]
S163 T163 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S176 G176 Biomuta DOID:1324 / lung cancer [ cosmic ]
K326 N326 Biomuta DOID:363 / uterine cancer [ icgc ]
T341 I341 Biomuta DOID:4159 / skin cancer [ cosmic ]