iPTMnet Report for Q99442 (SEC62)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99442 / SEC62_HUMAN
Protein Name Translocation protein SEC62
Gene Name Name: SEC62
Synonyms:TLOC1;
Organism Homo sapiens (Human)

PRO ID PR:Q99442
DAG View
PRO Name translocation protein SEC62 (human)
Definition A translocation protein SEC62 that is encoded in the genome of human.
Short Label hSEC62
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99442 (SEC62) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Ubiquitination PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
Y46 Phosphorylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
C55 Methylation IEDB 31844290
K60 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K110 Acetylation PhosphoSitePlus
K114 Acetylation PhosphoSitePlus
S117 Phosphorylation HPRD   PhosphoSitePlus 20068231
K119 Acetylation PhosphoSitePlus
K123 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
T135 O-Glycosylation GlyGen 35138101, 30620550
K141 Acetylation PhosphoSitePlus
K143 Acetylation PhosphoSitePlus
T155 Phosphorylation HPRD   PhosphoSitePlus 20068231
T158 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 17081983, 20068231
S237 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
S313 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 17081983
T332 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus   UniProt 24275569
S341 Phosphorylation PhosphoSitePlus   UniProt 23186163
T343 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
S345 Phosphorylation PhosphoSitePlus
S353 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692
S356 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692, 23186163
S357 Phosphorylation HPRD   PhosphoSitePlus 19651622
T367 Phosphorylation PhosphoSitePlus
T375 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18318008, 23186163, 18452278
T391 Phosphorylation PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K26 N26 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
C55 F55 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K134 N134 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T135 K135 Biomuta DOID:1319 / brain cancer [ cosmic ]
K143 T143 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S309 N309 Biomuta DOID:4159 / skin cancer [ cosmic ]
T367 I367 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T367 A367 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]