iPTMnet Report for Q99435 (NELL2)
Protein Information
| UniProt AC / UniProt ID | Q99435 / NELL2_HUMAN |
| Protein Name | Protein kinase C-binding protein NELL2 precursor |
| Gene Name | Name: NELL2 Synonyms:NRP2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q99435 |
| PRO Name | protein kinase C-binding protein NELL2 (human) |
| Definition | A protein kinase C-binding protein NELL2 that is encoded in the genome of human. |
| Short Label | hNELL2 |
| Category | organism-gene |
DAG ViewQ99435 (NELL2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N53 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| T273 | O-Glycosylation | score1 | GlyGen | 29237092 | ||
| T275 | O-Glycosylation | score1 | GlyGen | 29237092 | ||
| Y350 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y359 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T770 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N53 | D53 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T273 | S273 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic, icgc ] | |
| T770 | N770 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T770 | I770 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] |
