iPTMnet Report for Q99259 (GAD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99259 / DCE1_HUMAN
Protein Name Glutamate decarboxylase 1
Gene Name Name: GAD1
Synonyms:GAD,GAD67;
Organism Homo sapiens (Human)

PRO ID PR:Q99259
DAG View
PRO Name glutamate decarboxylase 1 (human)
Definition A glutamate decarboxylase 1 that is encoded in the genome of human.
Short Label hGAD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99259 (GAD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K60 Ubiquitination PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
T91 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   RLIMS-P 15147202
Y265 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T91 Phosphorylation Q02156 (PRKCE) HPRD 15147202
S571 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
T91 Phosphorylation Q02156 (PRKCE) HPRD 15147202


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K60 N60 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K74 N74 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
Y265 C265 Biomuta DOID:2531 / hematologic cancer [ cosmic ]