Protein Information

Cytoscape View

UniProt AC / UniProt ID Q99062 / CSF3R_HUMAN
Protein Name Granulocyte colony-stimulating factor receptor precursor
Gene Name Name: CSF3R
Organism Homo sapiens (Human)

PRO ID PR:Q99062
DAG View
PRO Name granulocyte colony-stimulating factor receptor (human)
Definition A granulocyte colony-stimulating factor receptor that is encoded in the genome of human.
Short Label hCSF3R
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q99062 (CSF3R) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
N134 N-Glycosylation GlyGen   UniProt 16492764
Y196 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
K655 Ubiquitination PhosphoSitePlus
K695 Ubiquitination PhosphoSitePlus
K704 Ubiquitination PhosphoSitePlus
K705 Ubiquitination PhosphoSitePlus
Y727 Phosphorylation IntAct   phospho.ELM   PhosphoSitePlus 9864141, 12133942
Y752 Phosphorylation phospho.ELM   PhosphoSitePlus 9790917
Y767 Phosphorylation IntAct   phospho.ELM   PhosphoSitePlus 9864141, 9790917
T781 Phosphorylation PhosphoSitePlus
S783 Phosphorylation PhosphoSitePlus
Y787 Phosphorylation phospho.ELM   PhosphoSitePlus 8547634
Site PTM Type PTM Enzyme Score Source PMID
Y752 Phosphorylation P08631 (HCK) HPRD 9790917
Y787 Phosphorylation P08631 (HCK) HPRD 9790917
Site PTM Type PTM Enzyme Score Source PMID
Y779 Phosphorylation P08631 (HCK) HPRD 9790917
Y814 Phosphorylation P08631 (HCK) HPRD 9790917

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q99062 (CSF3R) Y727 P40763 (STAT3) unknown eFIP 9864141

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y196 H196 Biomuta DOID:1909 / melanoma [ cosmic ]
Y196 * Biomuta DOID:3571 / liver cancer [ icgc ]