iPTMnet Report for Q96TC7 (RMDN3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96TC7 / RMD3_HUMAN
Protein Name Regulator of microtubule dynamics protein 3
Gene Name Name: RMDN3
Synonyms:FAM82A2,FAM82C,PTPIP51;ORFNames:hucep-10,UNQ3122/PRO10274;
Organism Homo sapiens (Human)

PRO ID PR:Q96TC7
DAG View
PRO Name regulator of microtubule dynamics protein 3 (human)
Definition A regulator of microtubule dynamics protein 3 that is encoded in the genome of human.
Short Label hRMDN3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96TC7 (RMDN3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S44 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18220336
S46 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 18220336, 18669648, ...28754031, 19690332
S50 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
Y53 Phosphorylation PhosphoSitePlus
T54 Phosphorylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
T152 O-Glycosylation GlyGen 25813380
T152 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
T160 Phosphorylation UniProt 33124732
Y176 Phosphorylation PhosphoSitePlus   RLIMS-P 31075141, 22544307, 30139932, ...21513978, 28754031, 24970130, 24501773
Y176 Phosphorylation P12931 (SRC) PhosphoSitePlus 22544307
T177 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus   UniProt 24275569
S189 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus   UniProt 24275569
S201 Phosphorylation PhosphoSitePlus
C202 Methylation IEDB 31844290
K210 Sumoylation PhosphoSitePlus
S212 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 28754031, 18669648, 17081983, ...24275569
S221 Phosphorylation PhosphoSitePlus
S225 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S232 Phosphorylation PhosphoSitePlus   UniProt 24275569
S272 Phosphorylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
Y325 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
T388 Phosphorylation PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S44 Phosphorylation HPRD 19007248, 19691289, 19651622, ...18669648, 20166139, 20068231
S46 Phosphorylation HPRD 19413330, 18691976, 18578522, ...18491316, 18767875, 20058876, 19691289, 18452278, 19651622, 18669648, 20166139, 19415658, 20068231
S50 Phosphorylation HPRD 20166139, 18669648
S212 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231, 18452278
S221 Phosphorylation HPRD 17081983
S225 Phosphorylation HPRD 18669648
S318 Phosphorylation HPRD 19413330
Y325 Phosphorylation HPRD 19413330
S337 Phosphorylation HPRD 19413330


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q96TC7 (RMDN3) Y176 P04049 (RAF1) unknown eFIP 28754031
Phosphorylation Q96TC7 (RMDN3) S46 P04049 (RAF1) unknown eFIP 30360441


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S44 N44 Biomuta DOID:363 / uterine cancer [ cosmic ]
T152 I152 Biomuta DOID:4159 / skin cancer [ cosmic ]
S154 Y154 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc, tcga ]
S155 N155 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S156 C156 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S337 R337 Biomuta DOID:3571 / liver cancer [ cosmic ]