iPTMnet Report for Q96TA1 (NIBAN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96TA1 / NIBA2_HUMAN
Protein Name Protein Niban 2
Gene Name Name: NIBAN2
Synonyms:C9orf88,FAM129B;
Organism Homo sapiens (Human)

PRO ID PR:Q96TA1
DAG View
PRO Name protein Niban 2 (human)
Definition A protein Niban 2 that is encoded in the genome of human.
Short Label hNIBAN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96TA1 (NIBAN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 25255805, 25807930
K83 Ubiquitination PhosphoSitePlus
Y101 Phosphorylation PhosphoSitePlus
K104 Acetylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
T126 Phosphorylation PhosphoSitePlus
Y131 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K203 Acetylation PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
Y388 Phosphorylation PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
Y397 Phosphorylation PhosphoSitePlus
K401 Methylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
Y446 Phosphorylation PhosphoSitePlus
T450 Phosphorylation PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
R471 Methylation PhosphoSitePlus
R475 Methylation PhosphoSitePlus
K479 Acetylation PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
Y480 Phosphorylation PhosphoSitePlus
Y482 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
K507 Acetylation PhosphoSitePlus
T536 O-Glycosylation GlyGen 35008409, 34019948, 34725712, ...33465208, 28510447
K554 Ubiquitination PhosphoSitePlus
K561 Ubiquitination PhosphoSitePlus
Y565 Phosphorylation PhosphoSitePlus
S568 Phosphorylation PhosphoSitePlus   UniProt 20068231
S574 Phosphorylation PhosphoSitePlus   UniProt 18669648
Y593 Phosphorylation PhosphoSitePlus 26721396
Y593 Phosphorylation P00533 (EGFR) PhosphoSitePlus 26721396
S594 Phosphorylation PhosphoSitePlus
S596 Phosphorylation phospho.ELM 18669648
S601 Phosphorylation PhosphoSitePlus   UniProt 18669648
S603 Phosphorylation PhosphoSitePlus   UniProt 18669648
S605 Phosphorylation PhosphoSitePlus
T606 Phosphorylation PhosphoSitePlus   UniProt 18669648
S609 Phosphorylation PhosphoSitePlus   UniProt 18669648
T611 Phosphorylation PhosphoSitePlus
S613 Phosphorylation PhosphoSitePlus
S624 Phosphorylation PhosphoSitePlus   UniProt 19690332
S638 Phosphorylation PhosphoSitePlus   UniProt 18669648, 24275569
S641 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19362540, 19690332
S646 Phosphorylation PhosphoSitePlus   UniProt 17081983, 18669648, 24275569, ...19362540, 19690332, 20068231
T651 Phosphorylation PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...19362540, 19690332, 20068231
S681 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...19362540, 20068231
S691 Phosphorylation PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus   UniProt 23186163, 18669648, 24275569, ...19362540, 19690332
S696 Phosphorylation PhosphoSitePlus   UniProt 23186163, 18669648, 24275569, ...19362540, 19690332
S728 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S146 Phosphorylation HPRD 20068231
Y482 Phosphorylation HPRD 18083107
S568 Phosphorylation HPRD 18669648, 20068231
S574 Phosphorylation HPRD 18669648, 20068231
Y593 Phosphorylation HPRD 20068231
S594 Phosphorylation HPRD 18452278
S601 Phosphorylation HPRD 18669648, 17081983, 20068231
S603 Phosphorylation HPRD 18669648
S605 Phosphorylation HPRD 18669648
T606 Phosphorylation HPRD 18669648, 20068231
S609 Phosphorylation HPRD 18669648
T611 Phosphorylation HPRD 18669648
S613 Phosphorylation HPRD 20068231
S638 Phosphorylation HPRD 18669648, 17081983, 20068231
S641 Phosphorylation HPRD 18491316, 15302935, 19651622, ...18669648, 19415658, 20068231
S646 Phosphorylation HPRD 18491316, 17081983, 18452278, ...19651622, 18669648, 19415658, 20068231
T651 Phosphorylation HPRD 17081983, 20068231, 19415658
S665 Phosphorylation HPRD 19413330, 17322306, 18491316, ...18212344, 19651622, 18669648, 20166139, 19415658, 20068231
S681 Phosphorylation HPRD 19413330, 18491316, 17081983, ...19651622, 18669648, 19415658, 20068231
S691 Phosphorylation HPRD 19651622, 16083285, 18452278
S692 Phosphorylation HPRD 19413330, 18491316, 16964243, ...18767875, 15302935, 18452278, 19651622, 18669648, 18707149, 20166139, 19415658, 20068231
S696 Phosphorylation HPRD 19413330, 18491316, 16964243, ...18767875, 15302935, 18452278, 19651622, 18669648, 18707149, 20166139, 18212344
Site PTM Type PTM Enzyme Score Source PMID
S133 Phosphorylation HPRD 20068231
Y469 Phosphorylation HPRD 18083107
S555 Phosphorylation HPRD 18669648, 20068231
S561 Phosphorylation HPRD 18669648, 20068231
Y580 Phosphorylation HPRD 20068231
S581 Phosphorylation HPRD 18452278
S588 Phosphorylation HPRD 18669648, 17081983, 20068231
S590 Phosphorylation HPRD 18669648
S592 Phosphorylation HPRD 18669648
T593 Phosphorylation HPRD 18669648, 20068231
S596 Phosphorylation HPRD 18669648
T598 Phosphorylation HPRD 18669648
S600 Phosphorylation HPRD 20068231
S625 Phosphorylation HPRD 18669648, 17081983, 20068231
S628 Phosphorylation HPRD 18491316, 17081983, 19651622, ...18669648, 19415658, 20068231
S633 Phosphorylation HPRD 18491316, 17081983, 18452278, ...19651622, 18669648, 19415658, 20068231
T638 Phosphorylation HPRD 17081983, 20068231, 19415658
S652 Phosphorylation HPRD 19413330, 17322306, 18491316, ...18212344, 19651622, 18669648, 20166139, 19415658, 20068231
S668 Phosphorylation HPRD 19413330, 18491316, 17081983, ...19651622, 18669648, 19415658, 20068231
S678 Phosphorylation HPRD 19651622, 16083285, 18452278
S679 Phosphorylation HPRD 19413330, 17322306, 18491316, ...16964243, 18767875, 18452278, 19651622, 18669648, 18707149, 20166139, 19415658, 20068231
S683 Phosphorylation HPRD 19413330, 18491316, 16964243, ...18767875, 18452278, 19651622, 18669648, 16083285, 18707149, 20166139, 18212344


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S119 N119 Biomuta DOID:363 / uterine cancer [ icgc ]
Y131 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S138 F138 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T142 S142 Biomuta [ cosmic ]
T143 M143 Biomuta [ cosmic ] DOID:4362 / cervical cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K145 N145 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S315 F315 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y446 C446 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R475 Q475 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
R475 W475 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y480 H480 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T536 M536 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S561 R561 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S574 R574 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S581 I581 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S590 R590 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T593 P593 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S594 I594 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S596 L596 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S600 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S603 R603 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T606 P606 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S609 L609 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S613 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S679 L679 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S692 L692 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]