iPTMnet Report for Q96T49 (PPP1R16B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96T49 / PP16B_HUMAN
Protein Name Protein phosphatase 1 regulatory inhibitor subunit 16B precursor
Gene Name Name: PPP1R16B
Synonyms:ANKRD4,KIAA0823;
Organism Homo sapiens (Human)

PRO ID PR:Q96T49
DAG View
PRO Name protein phosphatase 1 regulatory inhibitor subunit 16B (human)
Definition A protein phosphatase 1 regulatory inhibitor subunit 16B that is encoded in the genome of human.
Short Label hPPP1R16B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96T49 (PPP1R16B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K36 Ubiquitination PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
C144 Methylation IEDB 31844290
C186 Methylation IEDB 31844290
C214 Methylation IEDB 31844290
K323 Ubiquitination PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus   RLIMS-P 23305203
S337 Phosphorylation PhosphoSitePlus   RLIMS-P 23305203
S350 Phosphorylation PhosphoSitePlus   UniProt 23186163
K360 Ubiquitination PhosphoSitePlus
Y382 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
Y435 Phosphorylation PhosphoSitePlus
Y437 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
S476 Phosphorylation IEDB   PhosphoSitePlus   UniProt 27920218, 23186163
K484 Ubiquitination PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
Y536 Phosphorylation PhosphoSitePlus
Y537 Phosphorylation PhosphoSitePlus
K550 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S56 G56 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K130 N130 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C186 R186 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S331 F331 Biomuta DOID:4159 / skin cancer [ cosmic ]
S333 R333 Biomuta DOID:363 / uterine cancer [ icgc ]
S350 N350 Biomuta DOID:4159 / skin cancer [ cosmic ]
S350 G350 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S476 N476 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K484 T484 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y537 C537 Biomuta DOID:10534 / stomach cancer [ cosmic ]