iPTMnet Report for Q96T21 (SECISBP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96T21 / SEBP2_HUMAN
Protein Name Selenocysteine insertion sequence-binding protein 2
Gene Name Name: SECISBP2
Synonyms:SBP2;
Organism Homo sapiens (Human)

PRO ID PR:Q96T21
DAG View
PRO Name selenocysteine insertion sequence-binding protein 2 (human)
Definition A selenocysteine insertion sequence-binding protein 2 that is encoded in the genome of human.
Short Label hSECISBP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96T21 (SECISBP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K15 Acetylation PhosphoSitePlus
R26 Methylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
R176 Methylation PhosphoSitePlus
Y184 Phosphorylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
C291 Methylation IEDB 31844290
S296 Phosphorylation PhosphoSitePlus
T307 Phosphorylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
S341 O-Glycosylation GlyGen 30379171, 29351928
S346 Phosphorylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
T424 Phosphorylation PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus
K533 Acetylation PhosphoSitePlus
K650 Ubiquitination PhosphoSitePlus
K662 Ubiquitination PhosphoSitePlus
K815 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K15 R15 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K15 N15 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R26 G26 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K126 N126 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K384 N384 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K384 R384 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S499 G499 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S499 R499 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]