iPTMnet Report for Q96ST8 (CEP89)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96ST8 / CEP89_HUMAN
Protein Name Centrosomal protein of 89 kDa
Gene Name Name: CEP89
Synonyms:CCDC123;
Organism Homo sapiens (Human)

PRO ID PR:Q96ST8
DAG View
PRO Name centrosomal protein of 89 kDa (human)
Definition A centrosomal protein of 89 kDa that is encoded in the genome of human.
Short Label hCEP89
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96ST8 (CEP89) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T35 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus   UniProt 19690332
S77 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
S114 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
Y157 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
K431 Ubiquitination PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
K541 Ubiquitination PhosphoSitePlus
K550 Ubiquitination PhosphoSitePlus
T560 Phosphorylation PhosphoSitePlus
K564 Ubiquitination PhosphoSitePlus
K642 Ubiquitination PhosphoSitePlus
S643 Phosphorylation PhosphoSitePlus
K664 Ubiquitination PhosphoSitePlus
K682 Ubiquitination PhosphoSitePlus
K698 Ubiquitination PhosphoSitePlus
K700 Ubiquitination PhosphoSitePlus
T739 Phosphorylation PhosphoSitePlus
T743 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S40 N40 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S114 C114 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S114 F114 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S144 R144 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S153 G153 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S153 I153 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]
K521 T521 Biomuta DOID:363 / uterine cancer [ icgc ]
K564 Q564 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S643 G643 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K698 N698 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T739 I739 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]