Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96SN7 / ORAI2_HUMAN
Protein Name Protein orai-2
Gene Name Name: ORAI2
Synonyms:C7orf19,CBCIP2,TMEM142B;ORFNames:PP1729;
Organism Homo sapiens (Human)

PRO ID PR:Q96SN7
DAG View
PRO Name protein orai-2 (human)
Definition A protein orai-2 that is encoded in the genome of human.
Short Label hORAI2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96SN7 (ORAI2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
Y34 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 N2 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S2 I2 Biomuta DOID:363 / uterine cancer [ icgc ]
S49 L49 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]