iPTMnet Report for Q96SK2 (TMEM209)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96SK2 / TM209_HUMAN
Protein Name Transmembrane protein 209
Gene Name Name: TMEM209
Organism Homo sapiens (Human)

PRO ID PR:Q96SK2
DAG View
PRO Name transmembrane protein 209 (human)
Definition A transmembrane protein 209 that is encoded in the genome of human.
Short Label hTMEM209
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96SK2 (TMEM209) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus   UniProt 23186163
S11 Phosphorylation PhosphoSitePlus   UniProt 23186163
K18 Ubiquitination PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus   UniProt 18691976, 20068231
T103 Phosphorylation PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
T115 Phosphorylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
Y189 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y203 Phosphorylation PhosphoSitePlus
Y219 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus   UniProt 18669648
T224 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
T230 Phosphorylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
Y235 Phosphorylation PhosphoSitePlus
T237 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163, 20068231
K257 Ubiquitination PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus   UniProt 23186163
K287 Acetylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
Y291 Phosphorylation PhosphoSitePlus
K304 Acetylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
T537 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S98 Phosphorylation HPRD 18691976, 20068231
S196 Phosphorylation HPRD 18691976, 18669648, 20068231
S198 Phosphorylation HPRD 18691976, 18669648, 20068231
S201 Phosphorylation HPRD 18691976, 18669648, 20068231
Y203 Phosphorylation HPRD 18691976
Y219 Phosphorylation HPRD 19651622
S221 Phosphorylation HPRD 18691976, 18669648
S222 Phosphorylation HPRD 18669648, 20068231
T224 Phosphorylation HPRD 18669648
Y226 Phosphorylation HPRD 20068231
S228 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
S248 Phosphorylation HPRD 18691976, 20068231
S260 Phosphorylation HPRD 20068231
S263 Phosphorylation HPRD 20068231
S265 Phosphorylation HPRD 20068231
S269 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 G9 Biomuta DOID:363 / uterine cancer [ icgc ]
T103 A103 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T115 M115 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y219 C219 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S221 Y221 Biomuta DOID:363 / uterine cancer [ icgc ]
T224 N224 Biomuta DOID:363 / uterine cancer [ icgc ]
K257 N257 Biomuta [ cosmic ]
K257 R257 Biomuta DOID:184 / bone cancer [ cosmic ]
S278 F278 Biomuta DOID:4159 / skin cancer [ cosmic ]