iPTMnet Report for Q96SD1 (DCLRE1C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96SD1 / DCR1C_HUMAN
Protein Name Protein artemis
Gene Name Name: DCLRE1C
Synonyms:ARTEMIS;
Organism Homo sapiens (Human)

PRO ID PR:Q96SD1
DAG View
PRO Name protein artemis (human)
Definition A protein artemis that is encoded in the genome of human.
Short Label hDCLRE1C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96SD1 (DCLRE1C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T71 O-Glycosylation GlyGen 30059200
K157 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
Y264 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
Y322 Phosphorylation PhosphoSitePlus
T380 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
K494 Acetylation PhosphoSitePlus
S503 Phosphorylation neXtProt   PhosphoSitePlus   Signor 15574327, 1660029, 16874298
S503 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus   Signor 1660029, 16874298
S503 Phosphorylation Q13315 (ATM) neXtProt   PhosphoSitePlus   Signor 15574327, 16874298
S516 Phosphorylation neXtProt   PRO   PhosphoSitePlus   Signor 16600297, 19423708, 15574327, ...1660029, 16874298
S516 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus   Signor 16600297, 1660029, 16874298
S516 Phosphorylation Q13315 (ATM) neXtProt   PhosphoSitePlus   Signor 15574327, 16874298
S516 Phosphorylation Q13535 (ATR) PhosphoSitePlus 19423708
S518 Phosphorylation PhosphoSitePlus
S534 Phosphorylation neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
S534 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
S538 Phosphorylation neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
S538 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
S548 Phosphorylation neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
S548 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
S553 Phosphorylation neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
S553 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus 16600297, 1660029, 16874298
T601 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
T613 Phosphorylation PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus
S645 Phosphorylation neXtProt   PRO   PhosphoSitePlus   Signor   UniProt 15723659, 19423708, 16600297, ...15574327, 15468306, 1660029, 16874298
S645 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus   Signor 16600297, 1660029, 16874298
S645 Phosphorylation Q13315 (ATM) neXtProt   PhosphoSitePlus   Signor 15574327, 16874298
S645 Phosphorylation Q13535 (ATR) PhosphoSitePlus 19423708
S647 Phosphorylation PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus
T656 Phosphorylation PhosphoSitePlus
T676 Phosphorylation PhosphoSitePlus
K683 Acetylation PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus
T692 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T91 Phosphorylation HPRD 15723659
T91 Phosphorylation Q13315 (ATM) HPRD 15723659
T251 Phosphorylation HPRD 15723659
T251 Phosphorylation Q13315 (ATM) HPRD 15723659
S516 Phosphorylation HPRD 15723659
S516 Phosphorylation Q13315 (ATM) HPRD 15723659
S534 Phosphorylation HPRD 15723659
S534 Phosphorylation Q13315 (ATM) HPRD 15723659
S538 Phosphorylation HPRD 15723659
S538 Phosphorylation Q13315 (ATM) HPRD 15723659
S553 Phosphorylation HPRD 15723659
S553 Phosphorylation Q13315 (ATM) HPRD 15723659
S562 Phosphorylation HPRD 15723659
S562 Phosphorylation Q13315 (ATM) HPRD 15723659
S645 Phosphorylation HPRD 15723659
S645 Phosphorylation Q13315 (ATM) HPRD 15723659
Site PTM Type PTM Enzyme Score Source PMID
T131 Phosphorylation HPRD 15723659
T131 Phosphorylation Q13315 (ATM) HPRD 15723659
S396 Phosphorylation HPRD 15723659
S396 Phosphorylation Q13315 (ATM) HPRD 15723659
S414 Phosphorylation HPRD 15723659
S414 Phosphorylation Q13315 (ATM) HPRD 15723659
S418 Phosphorylation HPRD 15723659
S418 Phosphorylation Q13315 (ATM) HPRD 15723659
S433 Phosphorylation HPRD 15723659
S433 Phosphorylation Q13315 (ATM) HPRD 15723659
S442 Phosphorylation HPRD 15723659
S442 Phosphorylation Q13315 (ATM) HPRD 15723659
S525 Phosphorylation HPRD 15723659
S525 Phosphorylation Q13315 (ATM) HPRD 15723659
Site PTM Type PTM Enzyme Score Source PMID
T136 Phosphorylation HPRD 15723659
T136 Phosphorylation Q13315 (ATM) HPRD 15723659
S401 Phosphorylation HPRD 15723659
S401 Phosphorylation Q13315 (ATM) HPRD 15723659
S419 Phosphorylation HPRD 15723659
S419 Phosphorylation Q13315 (ATM) HPRD 15723659
S423 Phosphorylation HPRD 15723659
S423 Phosphorylation Q13315 (ATM) HPRD 15723659
S438 Phosphorylation HPRD 15723659
S438 Phosphorylation Q13315 (ATM) HPRD 15723659
S447 Phosphorylation HPRD 15723659
S447 Phosphorylation Q13315 (ATM) HPRD 15723659
S530 Phosphorylation HPRD 15723659
S530 Phosphorylation Q13315 (ATM) HPRD 15723659


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047141 (hDCLRE1C/Phos:1) pS516,pS645 PRO
PR:000047142 (hDCLRE1C/Phos:2) pS645 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S317 F317 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S414 F414 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S419 F419 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S433 N433 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S438 N438 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S518 L518 Biomuta DOID:3571 / liver cancer [ cosmic ]
S525 F525 Biomuta DOID:4159 / skin cancer [ cosmic ]
S530 F530 Biomuta DOID:4159 / skin cancer [ cosmic ]
S534 F534 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S548 N548 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S548 T548 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S553 N553 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S607 I607 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S625 R625 Biomuta DOID:1612 / breast cancer [ cosmic ]
S645 F645 Biomuta DOID:4159 / skin cancer [ cosmic ]
S647 N647 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S688 L688 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]