iPTMnet Report for Q96S99 (PLEKHF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96S99 / PKHF1_HUMAN
Protein Name Pleckstrin homology domain-containing family F member 1
Gene Name Name: PLEKHF1
Synonyms:APPD,LAPF,ZFYVE15;
Organism Homo sapiens (Human)

PRO ID PR:Q96S99
DAG View
PRO Name pleckstrin homology domain-containing family F member 1 (human)
Definition A pleckstrin homology domain-containing family F member 1 that is encoded in the genome of human.
Short Label hPLEKHF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96S99 (PLEKHF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K44 Acetylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K97 T97 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S227 F227 Biomuta DOID:1612 / breast cancer [ cosmic ]
S227 Y227 Biomuta DOID:9256 / colorectal cancer [ cosmic ]