iPTMnet Report for Q96RY7 (IFT140)
Protein Information
| UniProt AC / UniProt ID | Q96RY7 / IF140_HUMAN |
| Protein Name | Intraflagellar transport protein 140 homolog |
| Gene Name | Name: IFT140 Synonyms:KIAA0590,WDTC2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96RY7 |
| PRO Name | intraflagellar transport protein 140 homolog (human) |
| Definition | An intraflagellar transport protein 140 that is encoded in the genome of human. |
| Short Label | hIFT140 |
| Category | organism-gene |
Q96RY7 (IFT140) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T72 | Phosphorylation | score1 | IEDB | 35494241 | ||
| K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K150 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K179 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K188 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S208 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T213 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y216 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K323 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K336 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K353 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S360 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K366 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S388 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 35494241 | ||
| S405 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K590 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y602 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K634 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K644 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K733 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K770 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K799 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K813 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K821 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K877 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S922 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K926 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K951 | Acetylation | score1 | PhosphoSitePlus | |||
| K951 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1014 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1040 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1077 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1090 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1178 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1211 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1218 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1239 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1312 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1320 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1334 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1358 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T1434 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1443 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T72 | M72 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K187 | N187 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S360 | N360 | Biomuta | [ cosmic ] | |
| K634 | E634 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K634 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K634 | N634 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| Y1014 | S1014 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
DAG View