iPTMnet Report for Q96RW7 (HMCN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96RW7 / HMCN1_HUMAN
Protein Name Hemicentin-1 precursor
Gene Name Name: HMCN1
Synonyms:FIBL6;
Organism Homo sapiens (Human)

PRO ID PR:Q96RW7
DAG View
PRO Name hemicentin-1 (human)
Definition A hemicentin-1 that is encoded in the genome of human.
Short Label hHMCN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96RW7 (HMCN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K266 Ubiquitination PhosphoSitePlus
K285 Acetylation PhosphoSitePlus
K300 Acetylation PhosphoSitePlus
T512 Phosphorylation PhosphoSitePlus
T530 Phosphorylation PhosphoSitePlus
N573 N-Glycosylation GlyGen 23090970, 24190977
T646 Phosphorylation PhosphoSitePlus
S745 Phosphorylation PhosphoSitePlus
T746 Phosphorylation PhosphoSitePlus
S878 Phosphorylation PhosphoSitePlus
T883 Phosphorylation PhosphoSitePlus
S895 Phosphorylation PhosphoSitePlus
S1015 Phosphorylation PhosphoSitePlus
T1112 Phosphorylation PhosphoSitePlus
S1124 Phosphorylation PhosphoSitePlus
Y1351 Phosphorylation PhosphoSitePlus
S1630 Phosphorylation PhosphoSitePlus
Y1636 Phosphorylation PhosphoSitePlus
S1658 Phosphorylation PhosphoSitePlus
T1674 Phosphorylation PhosphoSitePlus
K1840 Acetylation PhosphoSitePlus
S1966 Phosphorylation PhosphoSitePlus
T1968 Phosphorylation PhosphoSitePlus
S2013 Phosphorylation PhosphoSitePlus
S2249 Phosphorylation PhosphoSitePlus
S2257 Phosphorylation PhosphoSitePlus
Y2267 Phosphorylation PhosphoSitePlus
T2372 Phosphorylation PhosphoSitePlus
S2496 Phosphorylation IEDB 35494241
S2738 Phosphorylation PhosphoSitePlus
T2740 Phosphorylation PhosphoSitePlus
N2887 N-Glycosylation GlyGen 29741879
K2888 Acetylation PhosphoSitePlus
S3645 Phosphorylation PhosphoSitePlus
T3654 Phosphorylation PhosphoSitePlus
T3691 Phosphorylation PhosphoSitePlus
S3695 Phosphorylation PhosphoSitePlus
S3721 Phosphorylation PhosphoSitePlus
Y3781 Phosphorylation PhosphoSitePlus
T3786 Phosphorylation PhosphoSitePlus
T3791 Phosphorylation PhosphoSitePlus
T4030 Phosphorylation PhosphoSitePlus
S4040 Phosphorylation PhosphoSitePlus
S4046 Phosphorylation PhosphoSitePlus
S5409 O-Glycosylation GlyGen 30379171, 28411811, 35254053
T5411 O-Glycosylation GlyGen 30379171, 28411811, 35254053
Site PTM Type PTM Enzyme Score Source PMID
S3721 Phosphorylation HPRD 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T512 I512 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T646 A646 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T746 A746 Biomuta DOID:3571 / liver cancer [ cosmic ]
S895 I895 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1015 F1015 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1112 N1112 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y1351 H1351 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
T1674 I1674 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T1968 A1968 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S2013 L2013 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2249 P2249 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2738 L2738 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K2888 E2888 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T3691 I3691 Biomuta DOID:4159 / skin cancer [ cosmic ]
S3721 N3721 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S3721 I3721 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S3721 R3721 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T3786 S3786 Biomuta DOID:1324 / lung cancer [ cosmic ]