Protein Information

Cytoscape View

UniProt AC / UniProt ID Q96RU3 / FNBP1_HUMAN
Protein Name Formin-binding protein 1
Gene Name Name: FNBP1
Organism Homo sapiens (Human)

DAG View
PRO Name formin-binding protein 1 (human)
Definition A formin-binding protein 1 that is encoded in the genome of human.
Short Label hFNBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q96RU3 (FNBP1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K27 Acetylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K51 Acetylation PhosphoSitePlus
K52 Acetylation PhosphoSitePlus
K57 Acetylation PhosphoSitePlus
K66 Acetylation PhosphoSitePlus   UniProt 19608861
K110 Acetylation PhosphoSitePlus   UniProt 19608861
K110 Ubiquitination PhosphoSitePlus
K122 Acetylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
Y234 Phosphorylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
Y287 Phosphorylation PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
T294 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S296 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 16964243, ...15302935, 15144186, 18669648, 24275569, 23186163, 20068231
S299 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17287340, 21406692
S301 Phosphorylation PhosphoSitePlus
S303 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K312 Ubiquitination PhosphoSitePlus
K320 Acetylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
S347 Phosphorylation phospho.ELM 18669648
S349 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S359 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
K364 Ubiquitination PhosphoSitePlus
K378 Acetylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
Y500 Phosphorylation PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus
T507 Phosphorylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
Y522 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
T523 Phosphorylation PhosphoSitePlus
T537 Phosphorylation PhosphoSitePlus
Y578 Phosphorylation PhosphoSitePlus
Y600 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T294 Phosphorylation HPRD 17287340, 20068231
S296 Phosphorylation HPRD 19413330, 17287340, 16964243, ...15302935, 19664995, 15144186, 19651622, 18669648, 18707149, 20166139, 20068231
S299 Phosphorylation HPRD 19413330, 18669648, 17287340
S303 Phosphorylation HPRD 18669648
S347 Phosphorylation HPRD 18669648
S349 Phosphorylation HPRD 18669648, 20068231
S351 Phosphorylation HPRD 20068231
S359 Phosphorylation HPRD 18669648, 20068231
Y522 Phosphorylation HPRD 15592455
Site PTM Type PTM Enzyme Score Source PMID
T393 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K51 Q51 Biomuta DOID:363 / uterine cancer [ tcga ]
K66 T66 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K187 E187 Biomuta DOID:363 / uterine cancer [ tcga ]
T288 N288 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T294 A294 Biomuta DOID:1909 / melanoma [ cosmic ]
S299 R299 Biomuta DOID:3571 / liver cancer [ icgc ]
S301 * Biomuta DOID:3571 / liver cancer [ icgc ]
S303 C303 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
Y500 F500 Biomuta DOID:1324 / lung cancer [ tcga ]
S517 N517 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
T537 M537 Biomuta DOID:1909 / melanoma [ cosmic ]