iPTMnet Report for Q96RE7 (NACC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96RE7 / NACC1_HUMAN
Protein Name Nucleus accumbens-associated protein 1
Gene Name Name: NACC1
Synonyms:BTBD14B,NAC1;
Organism Homo sapiens (Human)

PRO ID PR:Q96RE7
DAG View
PRO Name nucleus accumbens-associated protein 1 (human)
Definition A nucleus accumbens-associated protein 1 that is encoded in the genome of human.
Short Label hNACC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96RE7 (NACC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y54 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
T150 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus
K167 Sumoylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
C178 Methylation IEDB 31844290
K183 Ubiquitination PhosphoSitePlus
S188 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
K191 Ubiquitination PhosphoSitePlus
K202 Acetylation PhosphoSitePlus
K205 Acetylation PhosphoSitePlus
S263 Phosphorylation HPRD   PhosphoSitePlus 18452278
S274 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 15302935
S277 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 18452278
S330 Phosphorylation PhosphoSitePlus
K368 Ubiquitination PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
T424 Phosphorylation PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
K483 Sumoylation PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
Y489 Phosphorylation PhosphoSitePlus
K498 Ubiquitination PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P56524 (HDAC4) S246 Q96RE7 (NACC1) unknown eFIP 28319066


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S140 L140 Biomuta DOID:4159 / skin cancer [ cosmic ]
S141 L141 Biomuta DOID:363 / uterine cancer [ icgc ]
S151 L151 Biomuta DOID:10534 / stomach cancer [ cosmic ]