iPTMnet Report for Q96QV1 (HHIP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96QV1 / HHIP_HUMAN
Protein Name Hedgehog-interacting protein precursor
Gene Name Name: HHIP
Synonyms:HIP;ORFNames:UNQ5825/PRO19644;
Organism Homo sapiens (Human)

PRO ID PR:Q96QV1
DAG View
PRO Name hedgehog-interacting protein (human)
Definition A hedgehog-interacting protein that is encoded in the genome of human.
Short Label hHHIP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96QV1 (HHIP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K93 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
Y293 Phosphorylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
N447 N-Glycosylation GlyGen   UniProt 19561611
K472 Ubiquitination PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
Y616 Phosphorylation PhosphoSitePlus
T618 Phosphorylation PhosphoSitePlus
T620 Phosphorylation PhosphoSitePlus
K622 Ubiquitination PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus
K659 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K105 E105 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K252 T252 Biomuta DOID:4159 / skin cancer [ cosmic ]
K329 T329 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T620 M620 Biomuta [ cosmic ]
K622 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K659 N659 Biomuta DOID:9256 / colorectal cancer [ cosmic ]