iPTMnet Report for Q96QU8 (XPO6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96QU8 / XPO6_HUMAN
Protein Name Exportin-6
Gene Name Name: XPO6
Synonyms:KIAA0370,RANBP20;
Organism Homo sapiens (Human)

PRO ID PR:Q96QU8
DAG View
PRO Name exportin-6 (human)
Definition An exportin-6 that is encoded in the genome of human.
Short Label hXPO6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96QU8 (XPO6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
K93 Ubiquitination PhosphoSitePlus
T152 Phosphorylation PhosphoSitePlus
T153 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
T201 Phosphorylation PhosphoSitePlus   UniProt 19690332
T204 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 15302935, ...19690332
S208 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163, ...17081983
T210 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S211 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S214 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S219 Phosphorylation PhosphoSitePlus
S224 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
K288 Ubiquitination PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
R305 Methylation PhosphoSitePlus
R307 Methylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
T585 Phosphorylation PhosphoSitePlus
T647 Phosphorylation PhosphoSitePlus
T652 Phosphorylation PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus
C678 Methylation IEDB 31844290
K717 Ubiquitination PhosphoSitePlus
K766 Ubiquitination PhosphoSitePlus
T781 Phosphorylation PhosphoSitePlus
T788 Phosphorylation PhosphoSitePlus
T804 Phosphorylation PhosphoSitePlus
K891 Ubiquitination PhosphoSitePlus
S961 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S199 Phosphorylation HPRD 18691976, 17081983
T201 Phosphorylation HPRD 18691976, 17081983
T204 Phosphorylation HPRD 19413330, 18691976, 19651622, ...17322306, 18669648, 20068231
S208 Phosphorylation HPRD 19413330, 18691976, 19651622, ...17322306, 18669648, 20068231
T210 Phosphorylation HPRD 18691976, 18669648, 20068231
S211 Phosphorylation HPRD 18669648
S214 Phosphorylation HPRD 15302935
S224 Phosphorylation HPRD 18691976, 18669648
S961 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 P2 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
R305 C305 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R307 L307 Biomuta DOID:1324 / lung cancer [ cosmic ]
R307 W307 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S558 N558 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T781 I781 Biomuta DOID:363 / uterine cancer [ cosmic ]
T788 I788 Biomuta DOID:2021 / placenta cancer [ cosmic ]