iPTMnet Report for Q96QT6 (PHF12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96QT6 / PHF12_HUMAN
Protein Name PHD finger protein 12
Gene Name Name: PHF12
Synonyms:KIAA1523;
Organism Homo sapiens (Human)

PRO ID PR:Q96QT6
DAG View
PRO Name PHD finger protein 12 (human)
Definition A PHD finger protein 12 that is encoded in the genome of human.
Short Label hPHF12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96QT6 (PHF12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S125 Phosphorylation PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
T130 Phosphorylation PhosphoSitePlus
S131 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16565220, ...18669648, 19690332
S133 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S134 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 16565220
T136 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
T146 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
T166 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
C274 Methylation IEDB 31844290
K373 Ubiquitination PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
K467 Sumoylation PhosphoSitePlus
T472 O-Glycosylation GlyGen 28411811, 30397120, 32938750, ...35254053, 34019948, 20305658, 35289036
T532 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus   UniProt 23186163
T557 Phosphorylation PhosphoSitePlus   UniProt 23186163
T570 Phosphorylation PhosphoSitePlus   UniProt 23186163
T586 Phosphorylation PhosphoSitePlus
S617 O-Glycosylation GlyGen 34846842, 28411811, 30397120, ...35254053, 34019948, 20305658, 35289036
S623 O-Glycosylation GlyGen 28411811, 30397120, 35254053, ...34019948, 20305658, 35289036
S627 O-Glycosylation GlyGen 28411811, 30397120, 35254053, ...34019948, 20305658, 35289036
S639 O-Glycosylation GlyGen 34846842
T645 Phosphorylation PhosphoSitePlus
T655 Phosphorylation PhosphoSitePlus
S657 Phosphorylation PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
T671 O-Glycosylation GlyGen 28411811, 30397120, 35254053, ...34019948, 20305658, 35289036
T671 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...24275569
T683 O-Glycosylation GlyGen 28411811, 30397120, 35254053, ...34019948, 20305658, 35289036
T684 O-Glycosylation GlyGen 28411811, 30397120, 35254053, ...34019948, 20305658, 35289036
S691 Phosphorylation PhosphoSitePlus
K751 Ubiquitination PhosphoSitePlus
S769 Phosphorylation PhosphoSitePlus
T880 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S883 Phosphorylation PhosphoSitePlus
S884 Phosphorylation PhosphoSitePlus
K973 Ubiquitination PhosphoSitePlus
S977 Phosphorylation PhosphoSitePlus
K987 Ubiquitination PhosphoSitePlus
S989 Phosphorylation PhosphoSitePlus
K991 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T130 Phosphorylation HPRD 20068231
S131 Phosphorylation HPRD 19413330, 19691289, 16565220, ...18669648, 18452278, 20068231
S133 Phosphorylation HPRD 19413330, 18669648, 20068231
S134 Phosphorylation HPRD 18669648, 20068231, 16565220
T136 Phosphorylation HPRD 20068231
T586 Phosphorylation HPRD 20068231
T671 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231
T712 Phosphorylation HPRD 20068231
S715 Phosphorylation HPRD 20068231
S769 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T130 Phosphorylation HPRD 20068231
S131 Phosphorylation HPRD 19413330, 19691289, 16565220, ...18669648, 18452278, 20068231
S133 Phosphorylation HPRD 19413330, 18669648, 20068231
S134 Phosphorylation HPRD 18669648, 20068231, 16565220
T136 Phosphorylation HPRD 20068231
T586 Phosphorylation HPRD 20068231
T671 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S142 L142 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S162 G162 Biomuta DOID:3571 / liver cancer [ cosmic ]
T166 I166 Biomuta [ cosmic ]
T472 I472 Biomuta DOID:4159 / skin cancer [ cosmic ]
S555 G555 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T655 I655 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S662 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]
T671 A671 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K987 N987 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ]