iPTMnet Report Q96QT4 TRPM7

Protein Information

UniProt AC / UniProt ID	Q96QT4 / TRPM7_HUMAN
Protein Name	Transient receptor potential cation channel subfamily M member 7
Gene Name	Name: TRPM7 Synonyms:CHAK1,LTRPC7;
Organism	Homo sapiens (Human)

PRO ID	PR:Q96QT4 DAG View
PRO Name	transient receptor potential cation channel subfamily M member 7 (human)
Definition	A transient receptor potential cation channel subfamily M member 7 that is encoded in the genome of human.
Short Label	hTRPM7
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q96QT4 (TRPM7) as Substrate

Q96QT4

Expanded View

Site	PTM Type	PTM Enzyme	Score	Source	PMID
M1	Acetylation		score1	UniProt	20068231
S5	Phosphorylation		score0	RLIMS-P	21280599
T12	Phosphorylation		score0	HPRD	20068231
S57	Phosphorylation		score1	PhosphoSitePlus
K66	Ubiquitination		score1	PhosphoSitePlus
S101	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
K189	Ubiquitination		score1	PhosphoSitePlus
S233	Phosphorylation		score1	PhosphoSitePlus
K351	Ubiquitination		score1	PhosphoSitePlus
T523	Phosphorylation		score1	PhosphoSitePlus
S554	Phosphorylation		score1	PhosphoSitePlus
T555	Phosphorylation		score1	PhosphoSitePlus
K667	Ubiquitination		score1	PhosphoSitePlus
S764	Phosphorylation		score1	PhosphoSitePlus
Y776	Phosphorylation		score1	PhosphoSitePlus
T778	Phosphorylation		score1	PhosphoSitePlus
K827	Ubiquitination		score1	PhosphoSitePlus
S907	Phosphorylation		score1	PhosphoSitePlus
K1159	Ubiquitination		score1	PhosphoSitePlus
T1163	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
K1168	Acetylation		score1	PhosphoSitePlus
S1191	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1193	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1224	Phosphorylation		score0	RLIMS-P	30338939
S1230	Phosphorylation		score1	PhosphoSitePlus
S1239	Phosphorylation		score1	PhosphoSitePlus
K1253	Ubiquitination		score1	PhosphoSitePlus
S1255	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1258	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
T1265	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1269	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	30338939
S1271	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1287	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1358	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1361	Phosphorylation		score1	PhosphoSitePlus
S1386	Phosphorylation		score1	PhosphoSitePlus
S1387	Phosphorylation	Q96QT4 (TRPM7)	score4	PhosphoSitePlus UniProt	18365021, 23186163
S1390	Phosphorylation	Q96QT4 (TRPM7)	score4	PhosphoSitePlus UniProt	18365021, 23186163
S1395	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
S1396	Phosphorylation		score1	PhosphoSitePlus
S1404	Phosphorylation	Q96QT4 (TRPM7)	score4	HPRD PhosphoSitePlus UniProt	19413330, 19664994, 18365021, ...23186163
T1405	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1407	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1410	Phosphorylation		score1	PhosphoSitePlus
S1413	Phosphorylation		score1	PhosphoSitePlus
T1417	Phosphorylation		score1	PhosphoSitePlus
T1419	Phosphorylation		score1	PhosphoSitePlus
T1435	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1446	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
T1455	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1456	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1463	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1468	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
T1471	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
K1473	Methylation		score1	PhosphoSitePlus
K1473	Ubiquitination		score1	PhosphoSitePlus
S1476	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1477	Phosphorylation	Q96QT4 (TRPM7)	score4	HPRD phospho.ELM PhosphoSitePlus UniProt	18365021, 18669648, 23186163, ...17081983
T1482	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1488	Phosphorylation		score1	PhosphoSitePlus
S1493	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1500	Phosphorylation		score2	HPRD PhosphoSitePlus	20068231
S1504	Phosphorylation		score1	PhosphoSitePlus
T1505	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
T1508	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1513	Phosphorylation	Q96QT4 (TRPM7)	score4	HPRD PhosphoSitePlus	18365021, 15781465
S1527	Phosphorylation	Q96QT4 (TRPM7)	score4	PhosphoSitePlus UniProt	18365021, 23186163
S1533	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
T1537	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
T1542	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1543	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
T1551	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1567	Phosphorylation	Q96QT4 (TRPM7)	score4	PhosphoSitePlus RLIMS-P	18365021, 28220887
S1569	Phosphorylation	Q96QT4 (TRPM7)	score4	HPRD PhosphoSitePlus UniProt	18365021, 23186163, 15781465
T1583	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1598	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1615	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1660	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
T1685	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1695	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1779	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
T1830	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
K1833	Ubiquitination		score1	PhosphoSitePlus
S1851	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021
S1860	Phosphorylation	Q96QT4 (TRPM7)	score2	PhosphoSitePlus	18365021

Q96QT4 (TRPM7) as PTM Enzyme

Protein as Phosphorylation Enzyme

Substrate	Site	Score	Source	PMID
O00418 (EEF2K)	S78	score3	neXtProt PhosphoSitePlus	21112387
P04083 (ANXA1)	S5	score4	HPRD PhosphoSitePlus Signor	24103589, 15485879, 20068231
P28289 (TMOD1)	S2	score2	PhosphoSitePlus	19137675
P28289 (TMOD1)	T54	score2	PhosphoSitePlus	19137675
P35579 (MYH9)	T1800	score2	PhosphoSitePlus	18394644
P35579 (MYH9)	S1803	score2	PhosphoSitePlus	18394644
P35579 (MYH9)	S1808	score2	PhosphoSitePlus	18394644
Q96QT4 (TRPM7)	T1163	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1191	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1193	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1255	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1258	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1265	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1271	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1287	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1358	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1387	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1390	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1404	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1405	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1407	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1435	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1446	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1455	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1456	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1463	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1468	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1471	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1476	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1477	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1482	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1493	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1505	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1508	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1513	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1527	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1533	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1537	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1542	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1543	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1551	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1567	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1569	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1583	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1598	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1615	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1660	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1685	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1695	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1779	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	T1830	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1851	score2	PhosphoSitePlus	18365021
Q96QT4 (TRPM7)	S1860	score2	PhosphoSitePlus	18365021

PTM sites affected in variants

Site	Variant	Source	Disease [Sample source]
S5	F5	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S554	N554	Biomuta	DOID:4606 / bile duct cancer [ cosmic ]
K827	N827	Biomuta	DOID:363 / uterine cancer [ cosmic ]
K1168	R1168	Biomuta	DOID:363 / uterine cancer [ cosmic ]
S1224	*	Biomuta	DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S1386	T1386	Biomuta	DOID:1612 / breast cancer [ cosmic ]
S1387	P1387	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
S1387	*	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S1446	I1446	Biomuta	DOID:1324 / lung cancer [ cosmic ]
S1463	C1463	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic ]
S1468	P1468	Biomuta	DOID:1781 / thyroid gland cancer [ cosmic ]
S1477	Y1477	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
T1482	I1482	Biomuta	[ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S1660	N1660	Biomuta	DOID:1324 / lung cancer [ cosmic ]
T1830	M1830	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
S1860	Y1860	Biomuta	DOID:363 / uterine cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S1860	T1860	Biomuta	DOID:1324 / lung cancer [ cosmic ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q96QT4 (TRPM7)

Protein Information

Interactive Sequence View

Q96QT4 (TRPM7) as Substrate

Q96QT4 (TRPM7) as PTM Enzyme

PTM sites affected in variants