Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96QK1 / VPS35_HUMAN
Protein Name Vacuolar protein sorting-associated protein 35
Gene Name Name: VPS35
Synonyms:MEM3;ORFNames:TCCCTA00141;
Organism Homo sapiens (Human)

PRO ID PR:Q96QK1
DAG View
PRO Name vacuolar protein sorting-associated protein 35 (human)
Definition A vacuolar protein sorting-associated protein 35 that is encoded in the genome of human.
Short Label hVPS35
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96QK1 (VPS35) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 20068231
K14 Ubiquitination PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
Y67 Phosphorylation PhosphoSitePlus
R145 Methylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
T390 Phosphorylation HPRD   PhosphoSitePlus 20068231
S391 Phosphorylation HPRD 20068231
S392 Phosphorylation HPRD 20068231
K396 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
Y507 Phosphorylation PhosphoSitePlus
T512 Phosphorylation PhosphoSitePlus
K515 Acetylation PhosphoSitePlus
K555 Acetylation PhosphoSitePlus
K659 Ubiquitination PhosphoSitePlus
T683 Phosphorylation PhosphoSitePlus
K694 Acetylation PhosphoSitePlus
K694 Ubiquitination PhosphoSitePlus
K701 Acetylation PhosphoSitePlus
S714 Phosphorylation HPRD   PhosphoSitePlus 20068231
S759 Phosphorylation PhosphoSitePlus
S760 Phosphorylation PhosphoSitePlus
K768 Ubiquitination PhosphoSitePlus
S783 Phosphorylation HPRD   PhosphoSitePlus 19664994
Y791 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K14 N14 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
R145 M145 Biomuta DOID:363 / uterine cancer [ tcga ]
R145 K145 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K555 N555 Biomuta DOID:363 / uterine cancer [ tcga ]