iPTMnet Report for Q96QD8 (SLC38A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96QD8 / S38A2_HUMAN
Protein Name Sodium-coupled neutral amino acid symporter 2
Gene Name Name: SLC38A2
Synonyms:ATA2;
Organism Homo sapiens (Human)

PRO ID PR:Q96QD8
DAG View
PRO Name sodium-coupled neutral amino acid symporter 2 (human)
Definition A sodium-coupled neutral amino acid symporter 2 that is encoded in the genome of human.
Short Label hSLC38A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96QD8 (SLC38A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Ubiquitination PhosphoSitePlus
K3 Ubiquitination PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus   UniProt 18669648
S12 Phosphorylation PhosphoSitePlus   UniProt 18669648
S17 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
Y20 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus   UniProt 19690332
S24 Phosphorylation IEDB   PhosphoSitePlus 34433824
Y28 Phosphorylation PhosphoSitePlus
Y30 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K38 Methylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
Y41 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus   UniProt 23186163
K59 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
Y134 Phosphorylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
Y220 Phosphorylation PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation HPRD 19413330, 18669648, 17081983
S12 Phosphorylation HPRD 19413330, 18669648, 20068231
S17 Phosphorylation HPRD 18669648, 17081983, 20068231
S18 Phosphorylation HPRD 18669648, 17081983, 20068231
S19 Phosphorylation HPRD 18669648, 20068231
Y20 Phosphorylation HPRD 17016520, 15951569, 18669648, ...17389395, 20068231
S21 Phosphorylation HPRD 18669648, 17081983, 20068231
S22 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S24 Phosphorylation HPRD 18669648, 17081983
Y28 Phosphorylation HPRD 17081983
S39 Phosphorylation HPRD 20068231
Y41 Phosphorylation HPRD 18578522, 17389395, 17081983, ...18707149
S469 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K2 N2 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S10 I10 Biomuta DOID:1324 / lung cancer [ cosmic ]
S12 F12 Biomuta DOID:363 / uterine cancer [ cosmic ]
S17 N17 Biomuta DOID:5041 / esophageal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S22 F22 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S24 N24 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S39 N39 Biomuta DOID:1319 / brain cancer [ cosmic ]
K60 T60 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S320 R320 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]