iPTMnet Report for Q96Q45 (TMEM237)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96Q45 / TM237_HUMAN
Protein Name Transmembrane protein 237
Gene Name Name: TMEM237
Synonyms:ALS2CR4;
Organism Homo sapiens (Human)

PRO ID PR:Q96Q45
DAG View
PRO Name transmembrane protein 237 (human)
Definition A transmembrane protein 237 that is encoded in the genome of human.
Short Label hTMEM237
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96Q45 (TMEM237) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation PhosphoSitePlus   UniProt 23186163
T41 Phosphorylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
T44 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus   UniProt 23186163
T56 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
T131 Phosphorylation PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S49 Phosphorylation HPRD 18578522
S62 Phosphorylation HPRD 19651622, 17081983
Site PTM Type PTM Enzyme Score Source PMID
S41 Phosphorylation HPRD 18578522
S54 Phosphorylation HPRD 19651622, 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K42 Q42 Biomuta DOID:4159 / skin cancer [ cosmic ]
K209 N209 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K209 R209 Biomuta DOID:263 / kidney cancer [ cosmic ]