iPTMnet Report for Q96PZ2 (FAM111A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96PZ2 / F111A_HUMAN
Protein Name Serine protease FAM111A
Gene Name Name: FAM111A
Synonyms:KIAA1895;
Organism Homo sapiens (Human)

PRO ID PR:Q96PZ2
DAG View
PRO Name serine protease FAM111A (human)
Definition A serine protease FAM111A that is encoded in the genome of human.
Short Label hFAM111A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96PZ2 (FAM111A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K16 Ubiquitination PhosphoSitePlus
K20 Ubiquitination PhosphoSitePlus
Y24 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus   UniProt 23186163
S29 Phosphorylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
T81 Phosphorylation IEDB 32387766
T97 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
K116 Sumoylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
C290 Methylation IEDB 31844290
K304 Methylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
C407 Methylation IEDB 31844290
K480 Ubiquitination PhosphoSitePlus
K505 Ubiquitination PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
Y511 Phosphorylation PhosphoSitePlus
T568 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S26 C26 Biomuta DOID:1612 / breast cancer [ cosmic ]
S26 F26 Biomuta DOID:1324 / lung cancer [ cosmic ]
S62 L62 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T81 I81 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
K315 Q315 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K321 E321 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]