iPTMnet Report for Q96PX1 (RNF157)
Protein Information
| UniProt AC / UniProt ID | Q96PX1 / RN157_HUMAN |
| Protein Name | E3 ubiquitin ligase RNF157 |
| Gene Name | Name: RNF157 Synonyms:KIAA1917; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96PX1 |
| PRO Name | E3 ubiquitin ligase RNF157 (human) |
| Definition | An E3 ubiquitin ligase RNF157 that is encoded in the genome of human. |
| Short Label | hRNF157 |
| Category | organism-gene |
DAG ViewQ96PX1 (RNF157) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| G2 | Myristoylation | score1 | UniProt | 20213681 | ||
| Y252 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C301 | Methylation | score1 | IEDB | 31844290 | ||
| C638 | Methylation | score1 | IEDB | 31844290 | ||
| S660 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 28655764 | ||
| S661 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 28655764 | ||
| S662 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 28655764 | ||
| S663 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 28655764 |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q96PX1 (RNF157) | S663 | P12830 (CDH1) | unknown | eFIP | 28655764 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C301 | R301 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| C638 | Y638 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S661 | F661 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S662 | I662 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |
