iPTMnet Report for Q96PV6 (LENG8)
Protein Information
| UniProt AC / UniProt ID | Q96PV6 / LENG8_HUMAN |
| Protein Name | Leukocyte receptor cluster member 8 |
| Gene Name | Name: LENG8 Synonyms:KIAA1932; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96PV6 |
| PRO Name | leukocyte receptor cluster member 8 (human) |
| Definition | A leukocyte receptor cluster member 8 that is encoded in the genome of human. |
| Short Label | hLENG8 |
| Category | organism-gene |
Q96PV6 (LENG8) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| S63 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S69 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T247 | O-Glycosylation | score1 | GlyGen | 32938750 | ||
| S351 | Phosphorylation | score2 | IEDB UniProt | 32897882, 23186163 | ||
| C695 | Methylation | score1 | IEDB | 31844290 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T31 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K41 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S58 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S62 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S63 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S69 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K232 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K248 | Methylation | score1 | PhosphoSitePlus | |||
| K248 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K257 | Methylation | score1 | PhosphoSitePlus | |||
| K281 | Sumoylation | score1 | PhosphoSitePlus | |||
| T307 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S314 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R337 | Methylation | score1 | PhosphoSitePlus | |||
| R345 | Methylation | score1 | PhosphoSitePlus | |||
| R355 | Methylation | score1 | PhosphoSitePlus | |||
| R357 | Methylation | score1 | PhosphoSitePlus | |||
| S360 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K363 | Acetylation | score1 | PhosphoSitePlus | |||
| K363 | Methylation | score1 | PhosphoSitePlus | |||
| S375 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S376 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S377 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S378 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S379 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T380 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S382 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S384 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y408 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R435 | Methylation | score1 | PhosphoSitePlus | |||
| K474 | Acetylation | score1 | PhosphoSitePlus | |||
| T535 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T650 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y17 | H17 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T31 | M31 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S58 | P58 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S69 | N69 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
| K257 | R257 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| R345 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| R355 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S375 | N375 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| S375 | C375 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| S377 | F377 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S382 | F382 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S384 | F384 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R435 | W435 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View