iPTMnet Report for Q96PQ0 (SORCS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96PQ0 / SORC2_HUMAN
Protein Name VPS10 domain-containing receptor SorCS2 precursor
Gene Name Name: SORCS2
Synonyms:KIAA1329;
Organism Homo sapiens (Human)

PRO ID PR:Q96PQ0
DAG View
PRO Name VPS10 domain-containing receptor SorCS2 (human)
Definition A VPS10 domain-containing receptor SorCS2 that is encoded in the genome of human.
Short Label hSORCS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96PQ0 (SORCS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K11 Acetylation PhosphoSitePlus
S21 O-Glycosylation GlyGen 30459171
T65 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S133 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
T240 Phosphorylation PhosphoSitePlus
T267 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
N328 N-Glycosylation GlyGen 23090970, 24190977
Y471 Phosphorylation PhosphoSitePlus
T522 Phosphorylation PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus
Y540 Phosphorylation PhosphoSitePlus
S726 Phosphorylation PhosphoSitePlus
N830 N-Glycosylation GlyGen 29741879
S1034 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S133 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S136 R136 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S184 L184 Biomuta DOID:4159 / skin cancer [ cosmic ]
S223 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T240 I240 Biomuta DOID:4159 / skin cancer [ cosmic ]
T522 I522 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S726 P726 Biomuta DOID:9256 / colorectal cancer [ icgc ]