iPTMnet Report for Q96PP9 (GBP4)
Protein Information
| UniProt AC / UniProt ID | Q96PP9 / GBP4_HUMAN |
| Protein Name | Guanylate-binding protein 4 |
| Gene Name | Name: GBP4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96PP9 |
| PRO Name | guanylate-binding protein 4 (human) |
| Definition | A guanylate-binding protein 4 that is encoded in the genome of human. |
| Short Label | hGBP4 |
| Category | organism-gene |
DAG ViewQ96PP9 (GBP4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T303 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C325 | Methylation | score1 | IEDB | 31844290 | ||
| T401 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K404 | Acetylation | score1 | PhosphoSitePlus | |||
| S429 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T433 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| D460 | Methylation | score1 | IEDB | 25880248 | ||
| S537 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K567 | Acetylation | score1 | PhosphoSitePlus | |||
| S615 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K634 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T303 | S303 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K404 | Q404 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S429 | L429 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T433 | I433 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S435 | I435 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| D460 | N460 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
