iPTMnet Report for Q96PN7 (TRERF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96PN7 / TREF1_HUMAN
Protein Name Transcriptional-regulating factor 1
Gene Name Name: TRERF1
Synonyms:BCAR2,RAPA,TREP132;
Organism Homo sapiens (Human)

PRO ID PR:Q96PN7
DAG View
PRO Name transcriptional-regulating factor 1 (human)
Definition A transcriptional-regulating factor 1 that is encoded in the genome of human.
Short Label hTRERF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96PN7 (TRERF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K72 Sumoylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
Y122 Phosphorylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
S455 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus
S491 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 23186163
K509 Sumoylation PhosphoSitePlus
K522 Sumoylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
K544 Sumoylation PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
K640 Sumoylation PhosphoSitePlus
T709 Phosphorylation PhosphoSitePlus
S715 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
T743 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T746 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T748 Phosphorylation PhosphoSitePlus
S756 Phosphorylation PhosphoSitePlus
S758 Phosphorylation PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus
T767 Phosphorylation PhosphoSitePlus   UniProt 19690332
K812 Ubiquitination PhosphoSitePlus
S892 Phosphorylation PhosphoSitePlus
K907 Acetylation PhosphoSitePlus
K914 Acetylation PhosphoSitePlus
K917 Acetylation PhosphoSitePlus
S918 Phosphorylation IEDB 35494241
T954 Phosphorylation PhosphoSitePlus   UniProt 21406692
S955 Phosphorylation PhosphoSitePlus   UniProt 21406692
S1066 Phosphorylation PhosphoSitePlus
T1080 Phosphorylation PhosphoSitePlus
K1154 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S491 Phosphorylation HPRD 15302935, 19664995
T743 Phosphorylation HPRD 18669648, 20068231
T746 Phosphorylation HPRD 18669648
T748 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S379 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S379 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S540 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S540 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S379 F379 Biomuta DOID:4159 / skin cancer [ cosmic, cosmic, icgc, cosmic, icgc ]
S455 F455 Biomuta DOID:4159 / skin cancer [ cosmic ]
S491 F491 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S540 F540 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S715 R715 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S730 F730 Biomuta DOID:4159 / skin cancer [ cosmic ]
T746 M746 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S758 N758 Biomuta DOID:1324 / lung cancer [ cosmic ]
S892 F892 Biomuta DOID:4159 / skin cancer [ cosmic ]
S918 Y918 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1066 L1066 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]