iPTMnet Report for Q96PN6 (ADCY10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96PN6 / ADCYA_HUMAN
Protein Name Adenylate cyclase type 10
Gene Name Name: ADCY10
Synonyms:SAC;
Organism Homo sapiens (Human)

PRO ID PR:Q96PN6
DAG View
PRO Name adenylate cyclase type 10 (human)
Definition An adenylate cyclase type 10 that is encoded in the genome of human.
Short Label hADCY10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96PN6 (ADCY10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S59 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
Y63 Phosphorylation PhosphoSitePlus
Y268 Phosphorylation PhosphoSitePlus
Y285 Phosphorylation PhosphoSitePlus
Y318 Phosphorylation PhosphoSitePlus
Y420 Phosphorylation IEDB 33936100
Y421 Phosphorylation PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus
Y520 Phosphorylation PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus
T586 O-Glycosylation GlyGen 30379171, 34105348, 35254053
T783 Phosphorylation PhosphoSitePlus
T809 Phosphorylation PhosphoSitePlus
S810 Phosphorylation PhosphoSitePlus
S815 O-Glycosylation GlyGen 34105348
S815 Phosphorylation PhosphoSitePlus
S867 O-Glycosylation GlyGen 30379171, 34105348, 35254053
T1132 Phosphorylation PhosphoSitePlus
Y1134 Phosphorylation PhosphoSitePlus
Y1255 Phosphorylation PhosphoSitePlus
Y1258 Phosphorylation PhosphoSitePlus
Y1267 Phosphorylation PhosphoSitePlus
S1443 Phosphorylation PhosphoSitePlus
Y1459 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T809 Phosphorylation HPRD 17924679
S810 Phosphorylation HPRD 17924679


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y268 F268 Biomuta DOID:4159 / skin cancer [ cosmic ]
S456 C456 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S456 F456 Biomuta DOID:4159 / skin cancer [ cosmic ]
S456 Y456 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S523 N523 Biomuta [ cosmic ]
T586 A586 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S815 Y815 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y1255 C1255 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1443 F1443 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]