iPTMnet Report for Q96PK6 (RBM14)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96PK6 / RBM14_HUMAN
Protein Name RNA-binding protein 14
Gene Name Name: RBM14
Synonyms:SIP;
Organism Homo sapiens (Human)

PRO ID PR:Q96PK6
DAG View
PRO Name RNA-binding protein 14 (human)
Definition An RNA-binding protein 14 that is encoded in the genome of human.
Short Label hRBM14
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96PK6 (RBM14) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Sumoylation PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
C108 Methylation IEDB 31844290
K112 Acetylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K126 Sumoylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K135 Acetylation PhosphoSitePlus
K135 Sumoylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K138 Sumoylation PhosphoSitePlus
K140 Sumoylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
K149 Sumoylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
K153 Sumoylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
S161 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
K164 Acetylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
K167 Sumoylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
T206 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...18220336, 15302935, 15144186, 16565220, 18669648, 24275569, 20068231, 16964243
S215 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S220 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983
S225 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S225 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y226 Phosphorylation PhosphoSitePlus
T231 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 32938750, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
T231 Phosphorylation PhosphoSitePlus
T236 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
T236 Phosphorylation PhosphoSitePlus
Y237 Phosphorylation PhosphoSitePlus
R238 Methylation PhosphoSitePlus
S242 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 32938750, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S242 Phosphorylation PhosphoSitePlus   UniProt 23186163
S244 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 34925382, ...30620550, 31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 32938750, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S244 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y249 Phosphorylation PhosphoSitePlus
R250 Methylation PhosphoSitePlus
S254 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 32938750, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S254 Phosphorylation PhosphoSitePlus
S256 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S256 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Y261 Phosphorylation PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
T267 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y273 Phosphorylation PhosphoSitePlus
R274 Methylation PhosphoSitePlus
S278 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S278 Phosphorylation PhosphoSitePlus
S280 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 32938750, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S280 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y285 Phosphorylation PhosphoSitePlus
R286 Methylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
S301 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S363 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S364 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
Y365 Phosphorylation PhosphoSitePlus
T367 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S372 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S391 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S392 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
T438 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S444 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
Y498 Phosphorylation PhosphoSitePlus
T518 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 32938750, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
T518 Phosphorylation PhosphoSitePlus
S520 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S520 Phosphorylation PhosphoSitePlus   UniProt 23186163
S521 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S521 Phosphorylation PhosphoSitePlus
S523 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S523 Phosphorylation PhosphoSitePlus   UniProt 23186163
S527 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 32938750, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
S527 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y528 Phosphorylation PhosphoSitePlus
S539 Phosphorylation PhosphoSitePlus
Y548 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus
Y558 Phosphorylation PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
S562 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
S571 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T572 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 19690332, ...18220336
Y576 Phosphorylation PhosphoSitePlus
T579 Phosphorylation PhosphoSitePlus
S582 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16565220, 23186163, 17081983, ...18220336
S587 Phosphorylation PhosphoSitePlus
Y588 Phosphorylation PhosphoSitePlus
Y592 Phosphorylation PhosphoSitePlus
K593 Acetylation PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus
K594 Sumoylation PhosphoSitePlus
K594 Ubiquitination PhosphoSitePlus
S599 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 32870666, 35289036, 29351928, 22661428, 29237092, 34725712, 31373491, 32119511, 21158410, 32574038, 35132862, 20305658, 22121020, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 28510447, 34229054, 20068230
K600 Sumoylation PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
Y614 Phosphorylation PhosphoSitePlus
R615 Methylation PhosphoSitePlus
S618 Phosphorylation O14757 (CHEK1) phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 21851590, 20068231
S620 Phosphorylation PhosphoSitePlus   UniProt 23186163
S623 Phosphorylation PhosphoSitePlus   UniProt 23186163
S627 Phosphorylation O14757 (CHEK1) IEDB   PhosphoSitePlus   UniProt 23186163, 33936100, 21851590, ...30784271, 29493099, 27869121
T629 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
S631 Phosphorylation PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
Y635 Phosphorylation PhosphoSitePlus
S643 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
Y645 Phosphorylation PhosphoSitePlus
R647 Methylation PhosphoSitePlus
Y648 Phosphorylation PhosphoSitePlus
S649 Phosphorylation Q96GD4 (AURKB) phospho.ELM   PhosphoSitePlus   UniProt 22267324, 18669648, 23186163, ...18220336
S651 Phosphorylation PhosphoSitePlus
Y652 Phosphorylation PhosphoSitePlus
Y655 Phosphorylation PhosphoSitePlus
R657 Methylation PhosphoSitePlus
Y665 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S161 Phosphorylation HPRD 17081983, 20068231
T206 Phosphorylation HPRD 19413330, 18691976, 18212344, ...20058876, 19691289, 19664995, 17322306, 18669648, 19651622, 18707149, 20068231, 20068230
S215 Phosphorylation HPRD 17081983, 20068231
S220 Phosphorylation HPRD 19651622, 17081983, 20068231
S225 Phosphorylation HPRD 18669648, 20068231
Y226 Phosphorylation HPRD 17081983
S256 Phosphorylation HPRD 18669648, 18212344
Y261 Phosphorylation HPRD 20068231
S280 Phosphorylation HPRD 18212344
S560 Phosphorylation HPRD 20058876
S562 Phosphorylation HPRD 17525332, 20068231
S571 Phosphorylation HPRD 19413330, 18669648, 20058876, ...20068231
T572 Phosphorylation HPRD 19413330, 20058876, 15302935, ...19664995, 19007248, 18669648, 18452278, 20068231
S582 Phosphorylation HPRD 19651622, 18767875, 19691289, ...20068231, 16565220
S587 Phosphorylation HPRD 17081983
Y588 Phosphorylation HPRD 17081983
S618 Phosphorylation HPRD 17081983, 18212344, 19664995, ...18669648, 20166139, 20068231, 17924679
S620 Phosphorylation HPRD 17081983, 18212344
S623 Phosphorylation HPRD 20068231
S627 Phosphorylation HPRD 20068231
T629 Phosphorylation HPRD 17081983
Y645 Phosphorylation HPRD 20068231
S649 Phosphorylation HPRD 18669648, 19664995, 19691289


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y114 C114 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S225 C225 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T231 M231 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T236 I236 Biomuta DOID:4159 / skin cancer [ cosmic ]
R238 W238 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R250 S250 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T267 A267 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y273 * Biomuta DOID:4159 / skin cancer [ cosmic ]
Y273 C273 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
R274 C274 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]
S280 C280 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R286 S286 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y365 C365 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S372 F372 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y498 C498 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T518 S518 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S527 T527 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S560 F560 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T572 P572 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T579 P579 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
S582 F582 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y588 H588 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ icgc ]
S599 L599 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y614 C614 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R615 H615 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S623 L623 Biomuta [ cosmic ] DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]
S631 P631 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S632 L632 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y645 H645 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R647 L647 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R647 H647 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ] DOID:9256 / colorectal cancer [ icgc ]
S649 L649 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S651 P651 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y655 C655 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y655 * Biomuta DOID:363 / uterine cancer [ cosmic ]
R657 Q657 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R657 W657 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]