iPTMnet Report for Q96PD7 (DGAT2)
Protein Information
UniProt AC / UniProt ID | Q96PD7 / DGAT2_HUMAN |
Protein Name | Diacylglycerol O-acyltransferase 2 |
Gene Name | Name: DGAT2 ORFNames:HMFN1045,UNQ738/PRO1433; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96PD7 |
PRO Name | diacylglycerol O-acyltransferase 2 (human) |
Definition | A diacylglycerol O-acyltransferase 2 that is encoded in the genome of human. |
Short Label | hDGAT2 |
Category | organism-gene |
Q96PD7 (DGAT2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
S33 | Phosphorylation | score1 | PhosphoSitePlus | |||
S37 | Phosphorylation | score1 | PhosphoSitePlus | |||
K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
K260 | Methylation | score1 | PhosphoSitePlus | |||
Y306 | Phosphorylation | score1 | PhosphoSitePlus | |||
S331 | Phosphorylation | score1 | PhosphoSitePlus | |||
K376 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K146 | N146 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S331 | F331 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |