Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96P50 / ACAP3_HUMAN
Protein Name Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3
Gene Name Name: ACAP3
Synonyms:CENTB5,KIAA1716;
Organism Homo sapiens (Human)

PRO ID PR:Q96P50
DAG View
PRO Name Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (human)
Definition An Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 that is encoded in the genome of human.
Short Label hACAP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96P50 (ACAP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
T247 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
T393 Phosphorylation PhosphoSitePlus
T395 Phosphorylation PhosphoSitePlus
R396 Methylation PhosphoSitePlus
R398 Methylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
K494 Ubiquitination PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S388 Phosphorylation HPRD 19651622
T393 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T247 K247 Biomuta DOID:3571 / liver cancer [ icgc ]
T386 M386 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S388 I388 Biomuta DOID:1324 / lung cancer [ cosmic ]
R396 W396 Biomuta DOID:1612 / breast cancer [ icgc ]
K504 N504 Biomuta DOID:1324 / lung cancer [ cosmic ]