Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96P48 / ARAP1_HUMAN
Protein Name Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
Gene Name Name: ARAP1
Synonyms:CENTD2,KIAA0782;
Organism Homo sapiens (Human)

PRO ID PR:Q96P48
DAG View
PRO Name Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (human)
Definition An Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 that is encoded in the genome of human.
Short Label hARAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96P48 (ARAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S42 Phosphorylation PhosphoSitePlus
T44 Phosphorylation PhosphoSitePlus
T69 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
T78 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
T173 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus   UniProt 18669648
Y231 Phosphorylation Q13882 (PTK6) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 20554524
S265 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus
Y345 Phosphorylation PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus   UniProt 17081983
Y359 Phosphorylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
Y367 Phosphorylation PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S429 Phosphorylation PhosphoSitePlus
Y431 Phosphorylation PhosphoSitePlus   UniProt 18669648
S497 Phosphorylation PhosphoSitePlus
T502 Phosphorylation PhosphoSitePlus
Y504 Phosphorylation PhosphoSitePlus   UniProt 23186163
S513 Phosphorylation PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
T722 O-Glycosylation GlyGen 29351928
S729 Phosphorylation PhosphoSitePlus
Y737 Phosphorylation PhosphoSitePlus
S738 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T743 Phosphorylation PhosphoSitePlus
S745 Phosphorylation PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus
Y751 Phosphorylation PhosphoSitePlus
K752 Ubiquitination PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
Y783 Phosphorylation PhosphoSitePlus
T791 Phosphorylation PhosphoSitePlus
Y828 Phosphorylation PhosphoSitePlus
K871 Ubiquitination PhosphoSitePlus
Y975 Phosphorylation PhosphoSitePlus
Y992 Phosphorylation PhosphoSitePlus
K1000 Ubiquitination PhosphoSitePlus
S1007 Phosphorylation PhosphoSitePlus
K1018 Ubiquitination PhosphoSitePlus
K1032 Ubiquitination PhosphoSitePlus
T1044 Phosphorylation PhosphoSitePlus
S1055 Phosphorylation PhosphoSitePlus
Y1219 Phosphorylation PhosphoSitePlus
Y1268 Phosphorylation PhosphoSitePlus
S1271 Phosphorylation PhosphoSitePlus
K1335 Ubiquitination PhosphoSitePlus
S1419 Phosphorylation PhosphoSitePlus
R1426 Methylation PhosphoSitePlus
S1428 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1435 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19690332
S1445 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
S4 Phosphorylation PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T109 Phosphorylation HPRD 17081983
S183 Phosphorylation HPRD 18669648, 20068231
Y186 Phosphorylation HPRD 18669648, 20068231
Y492 Phosphorylation HPRD 17081983
Y730 Phosphorylation HPRD 16497976
S1190 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T173 Phosphorylation HPRD 20068231
S229 Phosphorylation HPRD   phospho.ELM 19651622, 18669648, 17081983, ...20068231, 18220336
Y231 Phosphorylation HPRD   phospho.ELM 18669648, 17081983
T354 Phosphorylation HPRD 17081983
S428 Phosphorylation HPRD   phospho.ELM 18669648, 20068231, 18220336
S429 Phosphorylation phospho.ELM 18220336
Y431 Phosphorylation HPRD   phospho.ELM 18669648, 20068231
Y737 Phosphorylation HPRD 17081983
Y975 Phosphorylation HPRD 16497976
S1435 Phosphorylation HPRD   phospho.ELM 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S70 * Biomuta DOID:1612 / breast cancer [ icgc ]
T323 A323 Biomuta DOID:0070003 / blastoma [ cosmic ]
S342 F342 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S429 R429 Biomuta DOID:3571 / liver cancer [ icgc ]
T502 K502 Biomuta DOID:3571 / liver cancer [ icgc ]
T502 M502 Biomuta DOID:1793 / pancreatic cancer [ icgc, tcga ] DOID:10283 / prostate cancer [ cosmic ]
S513 * Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T743 A743 Biomuta DOID:363 / uterine cancer [ tcga ]
Y751 C751 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
Y828 N828 Biomuta DOID:1909 / melanoma [ cosmic ]
Y992 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y1219 C1219 Biomuta DOID:1324 / lung cancer [ cosmic ]
R1426 * Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1445 C1445 Biomuta DOID:1324 / lung cancer [ tcga ]