iPTMnet Report for Q96P47 (AGAP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96P47 / AGAP3_HUMAN
Protein Name Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3
Gene Name Name: AGAP3
Synonyms:CENTG3;
Organism Homo sapiens (Human)

PRO ID PR:Q96P47
DAG View
PRO Name Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (human)
Definition An Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 that is encoded in the genome of human.
Short Label hAGAP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96P47 (AGAP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S121 Phosphorylation PhosphoSitePlus
C183 Methylation IEDB 31844290
S219 Phosphorylation PhosphoSitePlus
C263 Methylation IEDB 31844290
S322 Phosphorylation PhosphoSitePlus
S323 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T324 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T326 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S332 Phosphorylation IEDB   PhosphoSitePlus 35494241
S336 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T340 Phosphorylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
K343 Methylation PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
T438 Phosphorylation PhosphoSitePlus
T442 Phosphorylation PhosphoSitePlus
S443 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 16964243
S450 Phosphorylation PhosphoSitePlus
S538 Phosphorylation PhosphoSitePlus   UniProt 23186163
S541 Phosphorylation PhosphoSitePlus
T634 Phosphorylation IEDB 35494241
S676 Phosphorylation PhosphoSitePlus
K732 Acetylation PhosphoSitePlus
Y825 Phosphorylation PhosphoSitePlus
S873 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T326 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y147 Phosphorylation HPRD 20068231
S157 Phosphorylation HPRD 20068231
S359 Phosphorylation HPRD 19413330, 18669648, 20068231
T360 Phosphorylation HPRD 19413330, 18669648
T362 Phosphorylation HPRD 18669648, 20068231
S372 Phosphorylation HPRD 18669648
T478 Phosphorylation HPRD 19413330, 19664995, 20068231
S479 Phosphorylation HPRD 16964243, 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y147 Phosphorylation HPRD 20068231
S157 Phosphorylation HPRD 20068231
S359 Phosphorylation HPRD 19413330, 18669648, 20068231
T360 Phosphorylation HPRD 19413330, 18669648
T362 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S121 Y121 Biomuta DOID:263 / kidney cancer [ cosmic ]
S157 Y157 Biomuta DOID:263 / kidney cancer [ cosmic ]
S336 C336 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S341 F341 Biomuta [ cosmic ]
S372 C372 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S443 R443 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S450 F450 Biomuta DOID:4159 / skin cancer [ cosmic ]
S479 R479 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
S541 F541 Biomuta DOID:4159 / skin cancer [ cosmic ]
S676 P676 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K732 R732 Biomuta DOID:263 / kidney cancer [ cosmic ]
S873 I873 Biomuta DOID:3571 / liver cancer [ cosmic ]