iPTMnet Report for Q96NM4 (TOX2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96NM4 / TOX2_HUMAN
Protein Name TOX high mobility group box family member 2
Gene Name Name: TOX2
Synonyms:C20orf100,GCX1;
Organism Homo sapiens (Human)

PRO ID PR:Q96NM4
DAG View
PRO Name TOX high mobility group box family member 2 (human)
Definition A TOX high mobility group box family member 2 that is encoded in the genome of human.
Short Label hTOX2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96NM4 (TOX2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S199 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
R357 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K329 Ubiquitination PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S201 L201 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K320 R320 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R357 Q357 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]