iPTMnet Report for Q96NE9 (FRMD6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96NE9 / FRMD6_HUMAN
Protein Name FERM domain-containing protein 6
Gene Name Name: FRMD6
Synonyms:C14orf31;
Organism Homo sapiens (Human)

PRO ID PR:Q96NE9
DAG View
PRO Name FERM domain-containing protein 6 (human)
Definition A FERM domain-containing protein 6 that is encoded in the genome of human.
Short Label hFRMD6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96NE9 (FRMD6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus
Y350 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
T401 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
Y412 Phosphorylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus
T523 Phosphorylation PhosphoSitePlus
S525 Phosphorylation PhosphoSitePlus
T529 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S544 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K553 Ubiquitination PhosphoSitePlus
S609 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y342 Phosphorylation HPRD 18491316
Y404 Phosphorylation HPRD   PhosphoSitePlus 17389395
S536 Phosphorylation HPRD 19651622, 18691976, 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T386 P386 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S426 L426 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S522 I522 Biomuta DOID:3571 / liver cancer [ cosmic ]
S536 I536 Biomuta DOID:1319 / brain cancer [ icgc ]
S542 R542 Biomuta DOID:1324 / lung cancer [ cosmic ]
S544 I544 Biomuta DOID:1319 / brain cancer [ icgc ]
K553 R553 Biomuta [ cosmic ]
S609 F609 Biomuta DOID:1324 / lung cancer [ cosmic ]